Evidence map›Paper›PMID 42099132›Full record

ArticleJournal of neurotrauma2026

From Cortical Impact to Inattention: Real-Time Acetylcholine Disruption Links Brain Trauma to Attentional Deficits.

Eleni H Moschonas, Ellen M Annas, Veronica D Domyslawski, Hong J Young, Shamseldin A H Metwally, Haley E Capeci, Jeffrey P Cheng, Dandan Sun, Anthony E Kline, Corina O Bondi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurotrauma, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eleni H MoschonasSafar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Ellen M AnnasSafar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Veronica D DomyslawskiSafar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Hong J YoungDepartment of Statistics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Shamseldin A H MetwallySafar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Haley E CapeciSafar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Jeffrey P ChengSafar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Dandan SunDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Anthony E KlineSafar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Corina O BondiSafar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-5733-4912

Funding

Optimizing Environmental Enrichment to Model Preclinical NeurorehabilitationR01NS084967 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLINE, ANTHONY E. · 2014 to 2025
$3.7M
Neurobehavioral, cognitive, and mechanistic effects of intranasally administered neural stem cells and environmental enrichment after cortical impact injury in ratsR01NS121037 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GUTOVA, MARGARITA, KLINE, ANTHONY E. · 2021 to 2024
$2.0M
Traumatic brain injury and aging: targeting the cholinergic system for deficits in sustained attention and executive functionR01NS110609 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BONDI, CORINA OANA · 2020 to 2024
$2.0M
NINDS NIH HHS R01 NS084967NINDS NIH HHS R01 NS110609NINDS NIH HHS R01 NS121037
6 · The paper itself

Abstract

Attentional deficits are prevalent and persistent after traumatic brain injury (TBI), yet our understanding of their etiology is incomplete. In uninjured rats,

Indexed as

acetylcholinecontrolled cortical impactIMARISmicrodialysisprefrontal cortexsustained attention

Identifiers

PMID42099132
PMCPMC13614112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.