Evidence map›Paper›PMID 42099055›Full record

ArticleDevelopment and psychopathology2026

Neurophysiological sensitivity in early childhood: EEG aperiodic slope moderates the association between maternal anxiety and child internalizing symptoms.

Dashiell D Sacks, Viviane Valdes, April R Levin, Charles A Nelson, Michelle Bosquet Enlow

Abstract read
In one paragraph

Article in Development and psychopathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dashiell D SacksDepartment of Psychiatry and Behavioral Sciences, Boston Children's Hospital, Boston, USA.ORCID https://orcid.org/0000-0003-2842-1301
Viviane ValdesDivision of Developmental Medicine, Boston Children's Hospital, Boston, USA.ORCID https://orcid.org/0000-0001-5809-3877
April R LevinDepartment of Neurology, Boston Children's Hospital, Boston, USA.
Charles A NelsonDivision of Developmental Medicine, Boston Children's Hospital, Boston, USA.ORCID https://orcid.org/0000-0002-4723-247X
Michelle Bosquet EnlowDepartment of Psychiatry and Behavioral Sciences, Boston Children's Hospital, Boston, USA.ORCID https://orcid.org/0000-0003-2598-3894

Funding

The Development of Face ProcessingR01MH078829 · NIMH · BOSTON CHILDREN'S HOSPITAL · PI Michelle A Bosquet Enlow · 2006 to 2026
$14.8M
NIMH NIH HHS R01 MH078829
6 · The paper itself

Abstract

Maternal internalizing (anxiety and depressive) symptoms are a robust risk factor for the development of internalizing symptoms in offspring, yet the neurobiological mechanisms that influence this association remain relatively unexplored. The aperiodic "slope" of the EEG power spectrum (i.e., aperiodic exponent) is hypothesized to index the cortical excitatory-inhibitory balance and may serve as an early neurophysiological marker of mental health risk. In a prospective longitudinal cohort (

Indexed as

AnxietyChild of Impaired ParentsDepressionMother-Child RelationsMothersAdultChild, PreschoolElectroencephalographyFemaleHumansInfantLongitudinal StudiesMaleProspective StudiesAperiodic exponentchild psychopathologyearly childhoodEEGmaternal anxiety

Identifiers

PMID42099055
PMCPMC13225479

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.