Evidence map›Paper›PMID 42099017›Full record

ArticleThe Kaohsiung journal of medical sciences2026

Proteomic and Metabolomic Profiling Reveal Mitochondrial Transplantation-Mediated Reprogramming in Gastric Cancer Cells.

Ping-Chen Chen, Chen-Kai Liu, Ching-Chung Tsai, Erna Sulistyowati, Fu-An Li, Chung-Jung Liu, Deng-Chyang Wu, Shih-Hsuan Chou, Fu-Chen Kuo, Bin Huang

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Article in The Kaohsiung journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ping-Chen ChenDepartment of Biological Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan.
Chen-Kai LiuDepartment of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, Taiwan.
Ching-Chung TsaiCollege of Medicine, I-Shou University, Kaohsiung, Taiwan.ORCID https://orcid.org/0000-0001-5719-8730
Erna SulistyowatiFaculty of Medicine, Universitas Islam Malang, Malang, East Java, Indonesia.
Fu-An LiInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Chung-Jung LiuRegenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan.
Deng-Chyang WuRegenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan.
Shih-Hsuan ChouGraduate Institute of Biomedical and Pharmaceutical Science, Fu-Jen Catholic University, New Taipei City, Taiwan.
Fu-Chen KuoCollege of Medicine, I-Shou University, Kaohsiung, Taiwan.
Bin HuangDepartment of Biological Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan.

Funding

Kaohsiung Medical University KMU-TB114008Kaohsiung Medical University KMU-TC113A02Kaohsiung Medical University NPUST-KMU-114-P004National Science and Technology Council 109-2314-B-037-118National Science and Technology Council 110-2314-B-037-140National Science and Technology Council 111-2314-B-037-008
6 · The paper itself

Abstract

Mitochondria provide multiple functions for cellular physiology. Transplantation of mitochondria isolated from gastric epithelial cells GES-1 reducing the malignancy of gastric cancer cells AGS was previously reported. To elucidate the underlying mechanisms, TMT-based proteomic analysis coupling ingenuity pathway software prediction revealed that 257 upregulated and 34 downregulated proteins were implicated in 14 signaling pathways, including mitochondrial cell dysfunction (data became available from ProteomeXchange with identifier PXD061705). The upregulation of p53, Bax, p-Akt

Indexed as

gastric cancermetabolomicsmitochondrial transplantationproteomicspyruvate

Identifiers

PMID42099017
PMCPMC13399923

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.