Evidence map›Paper›PMID 42098971›Full record

SynthesisJournal of clinical nursing2026

Effectiveness of Nurse-Led Interventions in Older Adults With Mild Cognitive Impairment or Dementia: A Systematic Review and Meta-Analysis.

Wei Xu, Guangwei Zhang, Xuechun Bai, Sitao Zhang, Mingzhu Zhao, Haoying Liu, Wenxi Duan, Jiali Bai, Yingying Chen, Ye Luo and 2 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of clinical nursing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wei XuJilin University School of Nursing, Changchun, China.
Guangwei ZhangThe First Hospital of Jilin University, Changchun, China.
Xuechun BaiJilin University School of Nursing, Changchun, China.
Sitao ZhangJilin University School of Nursing, Changchun, China.
Mingzhu ZhaoJilin University School of Nursing, Changchun, China.
Haoying LiuJilin University School of Nursing, Changchun, China.
Wenxi DuanJilin University School of Nursing, Changchun, China.
Jiali BaiJilin University School of Nursing, Changchun, China.
Yingying ChenJilin University School of Nursing, Changchun, China.
Ye LuoJilin University School of Nursing, Changchun, China.
Li ChenJilin University School of Nursing, Changchun, China.ORCID https://orcid.org/0000-0001-9556-9053
Huiru YinJilin University School of Nursing, Changchun, China.ORCID https://orcid.org/0000-0001-6856-8274

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe rising prevalence of cognitive impairment has made it a critical public health priority. Nurses are central to chronic disease management, yet the efficacy of the interventions in older adults with cognitive disorders remains uncertain.

objectiveTo evaluate the efficacy of nurse-led interventions in older adults with cognitive disorders.

methodsA comprehensive search was conducted across seven electronic databases from their inception to August 2025. This meta-analysis focused on nurse-led interventions. The primary outcome was cognitive function, and secondary outcomes included depressive symptoms and quality of life. Due to the heterogeneity of the studies, we employed a random effects model for the meta-analysis.

resultsThe results indicated that nurse-led interventions significantly improved cognition (SMD = 0.64; 95% CI, 0.39-0.88; p < 0.05), substantially alleviated depressive symptoms (SMD = -0.32; 95% CI, -0.53-0.11; p < 0.05) and enhanced quality of life (QoL) (SMD = 0.40; 95% CI, 0.17-0.64; p < 0.05).

conclusionsThe results of this study indicate that nurse-led interventions are highly beneficial for elderly individuals with mild cognitive impairment (MCI) or dementia. In future research, it is necessary to comprehensively consider the roles that nurses undertake. They should play an active role in the recovery from chronic diseases. These findings provide an important basis for policymakers and clinicians.

trial registrationPROSPERO Registration number: CRD42024619016.

Indexed as

Cognitive DysfunctionDementiaAgedAged, 80 and overFemaleHumansMaleQuality of Life

Identifiers

PMID42098971
PMCPMC13431853

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.