Evidence map›Paper›PMID 42098722›Full record

SynthesisInternational journal for equity in health2026

Strategies to reach, involve, and maintain underserved populations in health intervention research: a systematic review of reviews.

Jeroen Pronk, Hristiyanna Ivanova, Zeena Harakeh, Annemarie Schuller, Pepijn van Empelen, Hilde van Keulen

Abstract readSystematic Review
In one paragraph

Synthesis in International journal for equity in health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jeroen PronkExpertise Group Child Health, The Netherlands Organization for Applied Scientific Research, Leiden, The Netherlands. jeroen.pronk@tno.nl.ORCID http://orcid.org/0000-0002-4397-6527
Hristiyanna IvanovaExpertise Group Child Health, The Netherlands Organization for Applied Scientific Research, Leiden, The Netherlands.ORCID http://orcid.org/0009-0009-0913-5845
Zeena HarakehExpertise Group Child Health, The Netherlands Organization for Applied Scientific Research, Leiden, The Netherlands.ORCID http://orcid.org/0000-0002-6571-4894
Annemarie SchullerExpertise Group Child Health, The Netherlands Organization for Applied Scientific Research, Leiden, The Netherlands.ORCID http://orcid.org/0000-0001-7759-2946
Pepijn van EmpelenExpertise Group Child Health, The Netherlands Organization for Applied Scientific Research, Leiden, The Netherlands.ORCID http://orcid.org/0000-0002-9809-7650
Hilde van KeulenExpertise Group Child Health, The Netherlands Organization for Applied Scientific Research, Leiden, The Netherlands.ORCID http://orcid.org/0000-0002-8194-3478

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCertain population subgroups, including people with lower socioeconomic status, racial and/or ethnic minorities, and individuals with lower literacy skills, face greater health challenges and participate significantly less in health intervention research. This leads to non-generalizable findings and interventions that fail to meet their needs. Despite the recognition of barriers, such as mistrust, limited access, and communication challenges in previous research, strategies to overcome these barriers are still insufficiently implemented. This review of reviews aimed to synthesize existing intervention strategies for improving the recruitment and retention of underserved populations in health intervention research across health domains and assess evidence on their effectiveness.

methodsA systematic review of existing reviews was conducted in three databases (i.e., PubMed, PsycINFO, and Scopus) to identify, summarize, and synthesize strategies used to reach, involve, and maintain underserved populations in health intervention research. The following inclusion criteria were applied: (systematic) reviews and/or meta-analyses published in English between January 2013 and January 2026, with a focus on strategies for the inclusion of underserved populations in health intervention research.

resultsA total of 18 reviews published between 2014 and 2026 met all inclusion criteria, the majority (N = 11) being systematic reviews. The findings revealed considerable overlap across reviews, underscoring that certain strategies are frequently used. A comprehensive summary of these strategies is provided, categorized based on their primary goal: (1) encouragement strategies to improve outreach to underserved populations, (2) facilitation strategies to improve their participation, and 3) retention strategies to maintain their participation. However, retention was rarely addressed as a primary focus in the included reviews.

conclusionsAfter integrating evidence across reviews from diverse health domains and underserved populations, the findings of this review of reviews highlight the importance of a multifaceted recruitment strategy that incorporates and/or combines approaches and serve goals throughout the health intervention research process. Researchers should: (1) tailor research materials, design and interaction methods, (2) collaborate with local organizations and healthcare providers, and (3) offer flexible participation options and incentives. Additionally, regular assessment and adaptation of the intervention materials are crucial to maintain participant engagement and improve the intervention's effectiveness.

Indexed as

Health Services ResearchPatient SelectionVulnerable PopulationsEvidence GapsHumansHard-to-reach populationsHealth interventionsInclusive researchRecruitmentRetentionReviewUnderserved populations

Identifiers

PMID42098722
PMCPMC13321629

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.