Evidence map›Paper›PMID 42098656›Full record

ArticleBMC ophthalmology2026

Laser peripheral iridectomy use in the unoperated eyes of hospitalised patients with primary angle-closure glaucoma in a national multicentre study in China.

Huiyan Mao, Kun Xiong, Yongzhen Yu, Qi'ao Zhang, Jinyuan Chen, Xue Yin, Dan Wang, Hong Sun, Xiaoli Xing, Guoping Duan and 26 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

36 authors.

Huiyan Mao *National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.
Kun Xiong *National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.
Yongzhen YuNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.
Qi'ao ZhangNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.
Jinyuan ChenDepartment of Ophthalmology, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350000, China.
Xue YinFirst Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215000, China.
Dan WangJilin Province People's Hospital, Changchun, Jilin, 130000, China.
Hong SunJiangsu Province People's Hospital, Nanjing, Jiangsu, 210000, China.
Xiaoli XingGlaucoma, Tianjin Medical University Eye Hospital, Tianjin, 300000, China.
Guoping DuanHunan Provincial People's Hospital, Changsha, Hunan, 410000, China.
Zhiyang JiaHebei General Hospital, Shijiazhuang, Hebei, 050000, China.
Jian JiangEye Center, Xiangya Hospital of Central South University, Changsha, Hunan, 410000, China.
Zhengzheng WuSichuan Provincial People's Hospital, Chengdu, Sichuan, 610000, China.
Li TangDepartment of Ophthalmology, West China Hospital of Sichuan University, Chengdu, Sichuan, 610000, China.
Peng LuLanzhou University Second Hospital, Lanzhou, Gansu, 730000, China.
Danyan LiuThe Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, Shijiazhuang, 050000, China.
Yajuan ZhengJilin University Second Hospital, Changchun, Jilin, 130000, China.
Lidong ZhuoLiaoyuan City Central Hospital, Liaoyuan, Jilin, 136000, China.
Sujie FanDepartment of Glaucoma, Handan City Eye Hospital, Handan, Hebei, 056000, China.
Xinying ZhangJilin Central General Hospital, Changchun, Jilin, 130000, China.
Weiwei LiuHuaiyin Hospital of Huai'an City, Huai'an, Jiangsu, 223001, China.
Yan DaiMianyang Central Hospital, Mianyang, Sichuan, 621000, China.
Hong ChenHebei Eye Hospital, Xingtai, Hebei, 054000, China.
Huadong XiangZhangjiajie People's Hospital, Zhangjiajie, Hunan, 427000, China.
Jingyi LvLixiang Eye Hospital of Soochow University, Suzhou, Jiangsu, 215000, China.
Yang YangYueyang Central Hospital, Yueyang, Hunan, 414000, China.
Jianjun MaDepartment of Ophthalmology, Gansu Provincial Hospital, Lanzhou, Gansu, 730000, China.
Jianfang YangZiyang Hospital of Traditional Chinese Medicine, Ziyang, Sichuan, 641300, China.
Xueli CaoBaiyin City Central Hospital, Baiyin, Gansu, 730900, China.
Tingting ZhouZhangye People's Hospital, Zhangye, Gansu, 734000, China.
Wenyi GuoOphthalmology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200000, China.
Guoxing LiNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.
Shaodan ZhangNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.
Xin SunSichuan University West China Hospital, Chengdu, Sichuan, 610000, China.
Mingguang HeState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
Yuanbo LiangNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China. yuanboliang@wmu.edu.cn.

Funding

Leading Scientific and Technological Innovation Talents in Zhejiang Province 2021R52012National Key Research and Development Project of China 2020YFC2008200
6 · The paper itself

Abstract

objectiveTo investigate the use of laser peripheral iridectomy (LPI) in the unoperated eyes of hospitalised patients with primary angle-closure glaucoma (PACG).

methodsThis was a national multi-centre retrospective study, and the sample was selected via multi-stage stratified random sampling from 26 hospitals. Data on LPI use were extracted from the electronic medical records (EMRs) of 5,404 PACG patients from 1 January 2011 to 31 December 2020. We used a generalised estimating equations (GEE) model to identify factors influencing LPI use.

resultsAmong 3,525 unoperated eyes of hospitalised PACG patients, 35.3% of these eyes received LPI during hospitalisation, and the usage rate was 35.1% and 36.0% in provincial-level or above and in city-level hospitals, respectively. In multivariable models, an intraocular pressure (IOP) of > 21 mmHg (OR = 0.915; 95% CI [0.875, 0.956]), moderate visual impairment (OR = 0.898; 95% CI [0.849, 0.949]) and severe visual impairment or blindness (OR = 0.755; 95% CI [0.717, 0.794]) were associated with a lower LPI usage rate in unoperated eyes. By contrast, patients treated in the northern region had a higher LPI usage rate in unoperated eyes (OR = 1.343; 95% CI [1.295, 1.393]).

conclusionsThe usage rate of LPI in the unoperated eyes of PACG patients is relatively low in China, especially among patients in the southern region, with higher IOP and worse visual impairment.

Indexed as

Glaucoma, Angle-ClosureIridectomyIrisLaser TherapyAgedChinaFemaleHospitalizationHumansIntraocular PressureMaleMiddle AgedRetrospective StudiesVisual AcuityLaser peripheral iridectomyMulti-centre studyPrimary angle-closure glaucoma

Identifiers

PMID42098656
PMCPMC13321662

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