Evidence map›Paper›PMID 42098647›Full record

ReviewBMC infectious diseases2026

Mycobacterium shinjukuense pulmonary disease in a young woman: a case report and literature review.

Siwei Gu, Chunlei Wang, Binghuai Lu, Xiaojing Cui

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Siwei GuCapital Medical University, Beijing, P.R. China.
Chunlei WangNational Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Laboratory of Clinical Microbiology, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, P.R. China.
Binghuai LuNational Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Laboratory of Clinical Microbiology, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, P.R. China.
Xiaojing CuiNational Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, No.2 Yinghuayuan East Street, Chaoyang, Beijing, P.R. China. cuixiaojing86@163.com.

Funding

Noncommunicable Chronic Diseases-National Science and Technology Major Project 2024ZD0523003
6 · The paper itself

Abstract

backgroundMycobacterium shinjukuense is a rare type of non-tuberculous mycobacterium (NTM) first reported in Japan. Reported cases of Mycobacterium shinjukuense pulmonary diseases are rare where hosts exhibited apparent risk factors for NTM infection. No consensus has been made on its treatment regimen. CASE PRESENTATION: We report a case of Mycobacterium shinjukuense pulmonary disease in a previously healthy young woman presented as focal bronchiectasis and nodules. The diagnosis was established with 16S rRNA sequencing on bronchoalveolar lavage fluid mycobacterium culture. The patient was successfully treated with a thrice-a-week regimen of azithromycin, isoniazid and rifampicin. Whole-exome sequencing revealed mutations in TNFRSF13B and TLR2.

conclusionThe presence of Mycobacterium shinjukuense pulmonary disease was confirmed in China. Macrolide, rifampicin and isoniazid was effective in treatment of Mycobacterium shinjukuense pulmonary disease. Genetic susceptibility to NTM should be considered in young patients without apparent risk factors.

Indexed as

Lung DiseasesMycobacterium Infections, NontuberculousNontuberculous MycobacteriaAdultAnti-Bacterial AgentsAzithromycinBronchoalveolar Lavage FluidChinaFemaleHumansIsoniazidRifampinRNA, Ribosomal, 16SToll-Like Receptor 2Anti-Bacterial AgentsAzithromycinIsoniazidRifampinRNA, Ribosomal, 16SToll-Like Receptor 2DiagnosisInfectionNon-tuberculous mycobacteriumTreatment

Identifiers

PMID42098647
PMCPMC13326539

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.