Evidence map›Paper›PMID 42098328›Full record

ArticleJournal of human hypertension2026

Hypertensive heart disease attributable to high BMI: global trends, gender disparities, and SDI-based inequalities (1990-2021).

Yiming Zhou, Yukang Mao, Minshan Zhong, Yuxuan Lou, Yang Hua, Wei Sun, Tingting Wu

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of human hypertension, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yiming Zhou *Department of Cardiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, China.
Yukang Mao *Department of Cardiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, China.
Minshan Zhong *Department of Cardiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, China.
Yuxuan LouDepartment of Cardiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, China.
Yang HuaDepartment of Cardiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, China.
Wei SunDepartment of Cardiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, China. weisun7919@njmu.edu.cn.ORCID http://orcid.org/0000-0003-0833-0445
Tingting WuDepartment of Cardiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, China. wutingting@jsph.org.cn.ORCID http://orcid.org/0000-0001-6739-070X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to provide insights crucial for achieving UN Sustainable Development Goal 3.4, this study attempts to evaluate the global burden of hypertensive heart disease (HHD) owing to high BMI, stratified by gender and SDI, from 1990 to 2021 and projects trends to 2051. Leveraging Global Burden of Disease 2021 data, we assessed HHD mortality and DALYs attributable to high BMI via DisMod-MR 2.1. Health inequalities were quantified using SII and CI, with Bayesian age-period-cohort modeling enabling gender-stratified projections. Global HHD deaths attributable to high BMI showed a relative change of 1.48 from 1990-2021, corresponding to an approximately 148% increase. Females experienced disproportionately higher mortality (relative change +1.4) and DALYs (relative change +1.12) than males. Southern sub-Saharan Africa recorded the steepest ASMR increase (relative change +0.54), while East Asia saw mortality surge (relative change +1.14). The escalating HHD burden from high BMI is a health inequality crisis, disproportionately affecting females and low-resource regions. This demands urgent tiered interventions and requires reconciling economic growth with health system resilience to address the underlying socioeconomic paradox.

Indexed as

Body Mass IndexGlobal Burden of DiseaseHealth InequitiesHypertensionSocial Determinants of HealthDisability-Adjusted Life YearsFemaleHeart DiseasesHumansMaleMiddle AgedObesitySex Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.