ArticleScientific reports2026
Analysis of two-year hearing outcomes and risk factors in newborns in the province with the highest annual birth rate in Türkiye.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This study aimed to evaluate risk factors for neonatal hearing loss among newborns referred to tertiary audiology centers and to investigate their association with confirmed hearing outcomes. A total of 1,869 newborns referred to tertiary audiology centers after failed newborn hearing screening or due to established risk factors between January 2021 and January 2023 were retrospectively evaluated using the OtoAccess database. The analysis was restricted to referred newborns rather than the entire birth cohort. During 2021-2022, a total of 113,665 births were recorded in Şanlıurfa, of which 1,869 newborns were referred for diagnostic evaluation at tertiary audiology centers. Hearing loss was detected in 8.4% of infants. Among newborns with at least one documented risk factor, 48 (3.5%) met the clinical criteria for cochlear implantation. Family history of hearing loss and syndromic disorders were significantly associated with neonatal hearing loss (p < 0.05). No statistically significant differences were observed between infants with and without hearing loss in terms of mechanical ventilation, ototoxic drug exposure, hyperbilirubinemia, neurodegenerative disease, TORCH infections, cerebral pathology, or maternal diseases. Nearly half of affected infants had severe-to-profound hearing loss, highlighting the importance of early cochlear implant evaluation in referred neonatal populations. Family history of hearing loss and syndromic disorders were identified as significant factors associated with neonatal hearing loss in this referral-based cohort. The high prevalence of consanguineous marriage in the region may be associated with the burden of familial hearing loss. Additionally, the occurrence of hearing loss in infants without identifiable risk factors underscores the importance of universal newborn hearing screening and timely referral to specialized audiology centers.
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