Evidence map›Paper›PMID 42098230›Full record

ArticleNature plants2026

A high-quality bread wheat genome unravels the adaptive evolution of wheat end-use quality.

Xinyou Cao, Jijin Zhang, Yafei Guo, Yuhong Huang, Lei Guo, Beirui Niu, Xin Gao, Jun Xu, Danping Li, Xiukun Liu and 14 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature plants, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Xinyou Cao *Crop Research Institute, Shandong Academy of Agricultural Sciences/National Engineering Research Center of Wheat and Maize/State Key Laboratory of Wheat Improvement/Key Laboratory of Wheat Biology and Genetic Improvement in North Yellow & Huai River Valley/Shandong Provincial Technology Innovation Center for Wheat, Jinan, China.ORCID http://orcid.org/0000-0001-8267-3273
Jijin Zhang *Laboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China. jijinzhang@genetics.ac.cn.ORCID http://orcid.org/0000-0002-3384-0167
Yafei GuoLaboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Yuhong HuangUniversity of Chinese Academy of Sciences, Beijing, China.ORCID http://orcid.org/0000-0001-8313-8803
Lei GuoCrop Research Institute, Shandong Academy of Agricultural Sciences/National Engineering Research Center of Wheat and Maize/State Key Laboratory of Wheat Improvement/Key Laboratory of Wheat Biology and Genetic Improvement in North Yellow & Huai River Valley/Shandong Provincial Technology Innovation Center for Wheat, Jinan, China.ORCID http://orcid.org/0009-0006-1490-4010
Beirui NiuLaboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Xin GaoCrop Research Institute, Shandong Academy of Agricultural Sciences/National Engineering Research Center of Wheat and Maize/State Key Laboratory of Wheat Improvement/Key Laboratory of Wheat Biology and Genetic Improvement in North Yellow & Huai River Valley/Shandong Provincial Technology Innovation Center for Wheat, Jinan, China.ORCID http://orcid.org/0000-0003-2029-4547
Jun XuLaboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Danping LiCrop Research Institute, Shandong Academy of Agricultural Sciences/National Engineering Research Center of Wheat and Maize/State Key Laboratory of Wheat Improvement/Key Laboratory of Wheat Biology and Genetic Improvement in North Yellow & Huai River Valley/Shandong Provincial Technology Innovation Center for Wheat, Jinan, China.ORCID http://orcid.org/0000-0002-0201-409X
Xiukun LiuCrop Research Institute, Shandong Academy of Agricultural Sciences/National Engineering Research Center of Wheat and Maize/State Key Laboratory of Wheat Improvement/Key Laboratory of Wheat Biology and Genetic Improvement in North Yellow & Huai River Valley/Shandong Provincial Technology Innovation Center for Wheat, Jinan, China.ORCID http://orcid.org/0009-0002-9539-0429
Zhiliang ZhangLaboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Lipeng KangLaboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Xuebing QiuLaboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Haosheng LiCrop Research Institute, Shandong Academy of Agricultural Sciences/National Engineering Research Center of Wheat and Maize/State Key Laboratory of Wheat Improvement/Key Laboratory of Wheat Biology and Genetic Improvement in North Yellow & Huai River Valley/Shandong Provincial Technology Innovation Center for Wheat, Jinan, China.ORCID http://orcid.org/0009-0004-1520-4986
Jianjun LiuCrop Research Institute, Shandong Academy of Agricultural Sciences/National Engineering Research Center of Wheat and Maize/State Key Laboratory of Wheat Improvement/Key Laboratory of Wheat Biology and Genetic Improvement in North Yellow & Huai River Valley/Shandong Provincial Technology Innovation Center for Wheat, Jinan, China.ORCID http://orcid.org/0000-0002-2290-2641
Baoxue ShanCrop Research Institute, Shandong Academy of Agricultural Sciences/National Engineering Research Center of Wheat and Maize/State Key Laboratory of Wheat Improvement/Key Laboratory of Wheat Biology and Genetic Improvement in North Yellow & Huai River Valley/Shandong Provincial Technology Innovation Center for Wheat, Jinan, China.ORCID http://orcid.org/0009-0005-1507-2335
Xiaoyan DuanCrop Research Institute, Shandong Academy of Agricultural Sciences/National Engineering Research Center of Wheat and Maize/State Key Laboratory of Wheat Improvement/Key Laboratory of Wheat Biology and Genetic Improvement in North Yellow & Huai River Valley/Shandong Provincial Technology Innovation Center for Wheat, Jinan, China.ORCID http://orcid.org/0009-0006-7136-5631
Congyang YiUniversity of Chinese Academy of Sciences, Beijing, China.
Yang LiuUniversity of Chinese Academy of Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-2748-4303
Meng JinLaboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Changbin YinLaboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-0950-8391
Jing WangLaboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-2924-9833
Zhendong ZhaoCrop Research Institute, Shandong Academy of Agricultural Sciences/National Engineering Research Center of Wheat and Maize/State Key Laboratory of Wheat Improvement/Key Laboratory of Wheat Biology and Genetic Improvement in North Yellow & Huai River Valley/Shandong Provincial Technology Innovation Center for Wheat, Jinan, China. zhaozhendong925@163.com.ORCID http://orcid.org/0009-0004-0754-3208
Fei LuLaboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China. flu@genetics.ac.cn.ORCID http://orcid.org/0000-0002-3596-1712

Funding

National Science Foundation of China | National Natural Science Foundation of China-Yunnan Joint Fund (NSFC-Yunnan Joint Fund) 32225038
6 · The paper itself

Abstract

Understanding the genetics of superior dough performance is essential for improving wheat end-use quality. Here we present a de novo assembly of the genome of JM44, a Chinese wheat cultivar known for its exceptional end-use quality. The JM44 genome achieved reference-level quality (with a quality value of 66.74), depicting a complete picture of complex regions containing gluten genes. Our microsynteny analysis across the Triticum-Aegilops complex showed that high-molecular-weight glutenin subunit loci are highly conserved, while low-molecular-weight glutenin subunits and α-/β-gliadins exhibited greater structural variation. These variable loci appear to have been preferentially selected by humans and contributed substantially to the evolution of wheat quality traits. Moreover, we observed that epistatic interactions between gluten genes are strong in modern cultivars but markedly weaker in landraces, indicating the importance of epistatic selection during modern breeding. Our findings shed light on the genomics and evolution of wheat quality traits, providing valuable guidance for future breeding efforts.

Indexed as

Genome, PlantTriticumAegilopsBiological EvolutionBreadEvolution, MolecularGlutensPlant BreedinggluteninGlutens

Identifiers

PMID42098230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.