Evidence map›Paper›PMID 42097882›Full record

ArticleLife science alliance2026

The role of Nrf2 in thyroid maturation and hormone synthesis in vertebrate models.

Pierre Gillotay, Sushant Bangru, Benjamin Dassy, Benoit Haerlingen, Meghna P Shankar, Barbara F Fonseca, Panos G Ziros, Sumeet P Singh, Gerasimos P Sykiotis, Mirian Romitti and 1 more

Abstract read
In one paragraph

Article in Life science alliance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pierre GillotayInstitut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Université Libre de Bruxelles (ULB), Brussels, Belgium.
Sushant BangruDuke Cell Biology department, Duke University, Durham, NC, USA.
Benjamin DassyInstitut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Université Libre de Bruxelles (ULB), Brussels, Belgium.ORCID 0000-0001-5234-6052
Benoit HaerlingenInstitut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Université Libre de Bruxelles (ULB), Brussels, Belgium.
Meghna P ShankarInstitut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Université Libre de Bruxelles (ULB), Brussels, Belgium.ORCID 0009-0005-9478-4348
Barbara F FonsecaInstitut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Université Libre de Bruxelles (ULB), Brussels, Belgium.
Panos G ZirosService of Endocrinology, Diabetology and Metabolism, Lausanne University Hospital and University of Lausanne (UNIL), Lausanne, Switzerland.ORCID 0000-0001-9326-9356
Sumeet P SinghInstitut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Université Libre de Bruxelles (ULB), Brussels, Belgium.ORCID 0000-0002-5154-3318
Gerasimos P SykiotisService of Endocrinology, Diabetology and Metabolism, Lausanne University Hospital and University of Lausanne (UNIL), Lausanne, Switzerland.ORCID 0000-0002-9565-4941
Mirian RomittiInstitut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Université Libre de Bruxelles (ULB), Brussels, Belgium mirian.romitti@ulb.be.
Sabine CostagliolaInstitut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Université Libre de Bruxelles (ULB), Brussels, Belgium sabine.costagliola@ulb.be.ORCID 0000-0002-6869-9941

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In vertebrates, the thyroid gland synthesizes hormones that act on almost all tissues and are essential for normal growth and metabolism. Thyroid hormone production relies on iodination of thyroglobulin and requires H

Indexed as

NF-E2-Related Factor 2Thyroid GlandThyroid HormonesAnimalsHydrogen PeroxideMiceOxidative StressThyroglobulinVertebratesZebrafishZebrafish ProteinsHydrogen PeroxideNF-E2-Related Factor 2ThyroglobulinThyroid HormonesZebrafish Proteins

Identifiers

PMID42097882
PMCPMC13153729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.