Evidence map›Paper›PMID 42097710›Full record

ArticleBMJ global health2026

Factors affecting access to and utilisation of intravenous iron to treat anaemia in pregnancy in Zomba, Malawi: a qualitative study.

Elisabeth Mamani-Mategula, Hana Sabanovic, Naomi Von Dinklage, Ebony Verbunt, Khic-Houy Prang, Effie Chipeta, Lucinda Manda-Taylor

Abstract read
In one paragraph

Article in BMJ global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elisabeth Mamani-MategulaDepartment of Health Systems and Policy, Kamuzu University of Health Sciences, Blantyre, Malawi elmamani027@gmail.com.ORCID 0009-0004-9238-5549
Hana SabanovicSchool of Population and Global Health, Centre for Health Policy, The University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-2759-8781
Naomi Von DinklagePopulation Health and Immunity Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.ORCID 0009-0002-1680-3126
Ebony VerbuntSchool of Population and Global Health, Centre for Health Policy, The University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0001-5711-6715
Khic-Houy PrangSchool of Population and Global Health, Centre for Health Policy, The University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0001-9194-6472
Effie ChipetaDepartment of Health Systems and Policy, Kamuzu University of Health Sciences, Blantyre, Malawi.ORCID 0000-0002-7925-3443
Lucinda Manda-TaylorDepartment of Health Systems and Policy, Kamuzu University of Health Sciences, Blantyre, Malawi.ORCID 0000-0001-8149-0897

Funding

The Bill and Melinda Gates Foundation INV-004505
6 · The paper itself

Abstract

backgroundAnaemia in pregnancy significantly increases the risk of maternal and neonatal complications. Oral iron supplementation, the standard treatment, is often poorly tolerated and associated with low adherence. Intravenous iron presents a rapid alternative, and we examined the factors influencing access to and utilisation of intravenous iron in treating anaemia in pregnancy within Malawi's primary healthcare system.

methodsWe conducted a qualitative study embedded with a clinical trial. We collected data through in-depth interviews (n=16) and focus group discussions (n=3) with pregnant women enrolled in the trial, those who withdrew and their husbands and caregivers. Interviews were audio-recorded, transcribed and analysed using a reflexive thematic approach in NVivo 12. Themes were mapped onto the supply and demand domains of the Patient-Centred Access to Healthcare framework.

resultsBarriers to access and utilisation operated across both supply-side and demand-side domains. On the supply side, limited service awareness, logistical constraints and unclear provider communication reduced engagement with intravenous iron. On the demand side, pregnant women's knowledge about anaemia, cultural norms, personal beliefs and social support shaped decision-making and ability to access care. Facilitators across both domains included patient-centred service delivery, clear and responsive provider communication and family or peer involvement in decision-making, which enhanced trust, understanding and uptake.

conclusionIn conclusion, our study demonstrates that patient-centred approaches are critical for improving health literacy, and strong health systems are essential for the effective delivery of intravenous iron intervention. Addressing supply and demand barriers is vital for optimising uptake of intravenous iron interventions, improving health system performance and ensuring equitable access to antenatal care interventions, ultimately improving the health outcomes for mother and child.

Indexed as

Anemia, Iron-DeficiencyHealth Services AccessibilityIronPregnancy Complications, HematologicAdministration, IntravenousAdultFemaleFocus GroupsHealth Knowledge, Attitudes, PracticeHumansInterviews as TopicMalawiPregnancyQualitative ResearchYoung AdultIronHealth Services AccessibilityMaternal healthQualitative study

Identifiers

PMID42097710
PMCPMC13157774

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.