Evidence map›Paper›PMID 42097705›Full record

ArticleBMJ global health2026

Potential impact of increasing physical activity on NCD mortality in the EU: pathways to SDG 3.4.1 by 2030.

Abdu Nafan Aisul Muhlis, Nour Mahrouseh, Carlos Alexandre Soares Andrade, José Chen-Xu, Terje Andreas Eikemo, Mirza Balaj, Mary Economou, Enkeleint A Mechili, Brigid Unim, Carl Michael Baravelli and 13 more

Abstract read
In one paragraph

Article in BMJ global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Abdu Nafan Aisul MuhlisDepartment of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.ORCID 0000-0001-7691-6080
Nour MahrousehDepartment of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Carlos Alexandre Soares AndradeDepartment of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
José Chen-XuComprehensive Health Research Centre, Public Health Research Centre, National School of Public Health, NOVA University of Lisbon, Lisbon, Portugal.ORCID 0000-0003-1238-1384
Terje Andreas EikemoCentre for Health Equity Analytics (CHAIN), Department of Sociology and Political Science, Norwegian University of Science and Technology (NTNU), Trondheim, Trøndelag, Norway.
Mirza BalajResearch Centre for Education and the Labour Market (ROA), Maastricht University, Maastricht, The Netherlands.
Mary EconomouDepartment of Nursing, School of Health Sciences, Cyprus University of Technology, Limassol, Cyprus.
Enkeleint A MechiliDepartment of Healthcare, Faculty of Health, University of Vlora, Vlora, Albania.
Brigid UnimDepartment of Cardiovascular, Endocrine-metabolic Diseases and Aging, Italian National Institute of Health, Rome, Italy.
Carl Michael BaravelliCentre for Disease Burden, Norwegian Institute of Public Health, Bergen, Norway.
Andreea BadacheSchool of Health Sciences, Örebro University, Örebro, Sweden.
Jeroen SpijkerUniversitat Internacional de Catalunya, Barcelona, Spain.
Jonila GabraniCenter for Scientific Research in Public Health, Faculty of Medical Technical Sciences, European University of Tirana, Tirana, Albania.ORCID 0000-0002-8732-8193
Rafael José VieiraMEDCIDS, Department of Community Medicine, Information, and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.
Brian LassenTechnical University of Denmark, Lyngby, Denmark.
Romana HaneefCERPOP, UMR1295, unite mixte INSERM, University of Toulouse, Toulouse, Occitanie, France.
Gülcan TecirliHealth Technology Assessment Department, Health Services General Directorate, Ministry of Health of Türkiye, Ankara, Türkiye.
Sarah CuschieriFaculty of Medicine and Surgery, University of Malta, Msida, Malta.
David Rojas-RuedaDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado, USA.ORCID 0000-0001-5854-2484
Hanno HovenDepartment of Social & Behavioral Sciences, Harvard T H Chan School of Public Health, Boston, Massachusetts, USA.
Ghenwa ChamouniDepartment of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Gabriella Laila TarekDepartment of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Orsolya VargaDepartment of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary varga.orsolya@med.unideb.hu.ORCID 0000-0001-8771-3975

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhysical inactivity affects 36.2% of adults in the European Union (EU), contributing substantially to the burden of non-communicable diseases (NCDs). The WHO's Global Action Plan on Physical Activity 2018-2030 targets a 15% relative reduction in physical inactivity by 2030, supporting Sustainable Development Goal (SDG) 3.4.1 to achieve over 30% reduction in premature NCD mortality. This study estimates the number of averted deaths, premature deaths and cause-specific NCD deaths averted if physical activity targets are achieved across EU countries.

methodsWe applied the WHO Preventable Risk Integrated ModEl using baseline physical activity and body mass index from waves 2 and 3 of the European Health Interview Survey. The counterfactual scenario modelled a 15% increase in metabolic equivalent of task hours/week of moderate-to-vigorous physical activity and a 15% relative reduction in the proportion of adults who are physically inactive across the EU.

findingsIncreased physical activity is associated with an estimated 24 178 premature deaths averted by 2030 (95% uncertainty interval (UI): 23 253-25 103), equivalent to 3.3% of premature NCD mortality. Overall, 107 108 deaths (95% UI: 102 479-111 737) across all ages could be prevented, representing 4.7% of total NCD deaths in EU member states.

interpretationIncreasing physical activity alone is unlikely to achieve the SDG 3.4.1 target of reducing premature NCD deaths by 2030. However, when combined with other WHO 'best buy' interventions, such as improved diet and reduced tobacco and alcohol use, this target could be attainable across the EU.

Indexed as

ExerciseMortality, PrematureNoncommunicable DiseasesAdultEuropean UnionFemaleHumansMaleMiddle AgedEpidemiologyGlobal HealthHealth policyMathematical modellingPrevention strategies

Identifiers

PMID42097705
PMCPMC13157740

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.