Evidence map›Paper›PMID 42097443›Full record

ArticleThe Journal of biological chemistry2026

Lipid transfer proteins and PI4KIIα generate a phosphoinositide-linked proteome.

Noah D Carrillo, Mo Chen, Poorwa Awasthi, Tianmu Wen, Xiangqin Chen, Giang Vu, Dhruv Brahmbhatt, Michael Herlihy, Benjamin B Minkoff, Michael Sussman and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Noah D CarrilloUniversity of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA; Department of Medicine, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA.
Mo ChenUniversity of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA.
Poorwa AwasthiUniversity of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA.
Tianmu WenUniversity of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA.
Xiangqin ChenUniversity of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA.
Giang VuUniversity of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA.
Dhruv BrahmbhattUniversity of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA; Department of Medicine, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA.
Michael HerlihyUniversity of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA; Department of Medicine, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA.
Benjamin B MinkoffCenter for Genomic Science Innovation, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Michael SussmanCenter for Genomic Science Innovation, University of Wisconsin-Madison, Madison, Wisconsin, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Vincent L CrynsUniversity of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA; Department of Medicine, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA. Electronic address: vlcryns@medicine.wisc.edu.
Richard A AndersonUniversity of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA. Electronic address: raanders@wisc.edu.

Funding

Molecular & Environmental Toxicology Pre-& Postdoctoral Training ProgramT32ES007015 · NIEHS · UNIVERSITY OF WISCONSIN-MADISON · PI CHRISTOPHER A BRADFIELD · 1985 to 2026
$11.5M
Phosphoinositide Signaling in the Cytosol and NucleusR35GM134955 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Richard A. Anderson · 2020 to 2026
$5.0M
Regulation of Nuclear Akt by p53, MDM2 and Phosphoinositide Lipids Roles in Oncogenic Transformation and Tumor ProgressionR01CA286492 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Richard A. Anderson, VINCENT L. CRYNS · 2024 to 2026
$2.8M
Department of Defense HT9425-23-1-0553Department of Defense HT9425-23-1-0554Department of Defense W81XWH-17-1-0258Department of Defense W81XWH-17-1-0259Department of Defense W81XWH-21-1-0129NCI NIH HHS R01 CA286492NIEHS NIH HHS T32 ES007015NIGMS NIH HHS R35 GM134955
6 · The paper itself

Abstract

Phosphoinositide (PIP

Indexed as

PhosphatidylinositolsPhospholipid Transfer ProteinsPhosphotransferases (Alcohol Group Acceptor)ProteomeAnimalsHumansMinor Histocompatibility AntigensSignal TransductionMinor Histocompatibility Antigensphosphatidylinositol phosphate 4-kinasePhosphatidylinositolsPhospholipid Transfer ProteinsPhosphotransferases (Alcohol Group Acceptor)ProteomeAktcell stressnucleusp53phosphatidylinositol transfer proteinPI3,4,5P(3)PI4,5P(2)PI 4-kinasePIP(n)-linked proteinspPhosphoinositide

Identifiers

PMID42097443
PMCPMC13266111

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.