Evidence map›Paper›PMID 42097304›Full record

ArticleBioinformatics (Oxford, England)2026

EMTscore infers divergent EMT pathways from omics data and enables rapid screening for EMT-associated gene sets.

Haimei Wen, Leonidas Bleris, Tian Hong

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Haimei WenDepartment of Biological Sciences, The University of Texas at Dallas, Richarson, TX 75080, United States.
Leonidas BlerisDepartment of Bioengineering, The University of Texas at Dallas, Richarson, TX 75080, United States.ORCID 0000-0002-6610-9020
Tian HongDepartment of Biological Sciences, The University of Texas at Dallas, Richarson, TX 75080, United States.ORCID 0000-0002-8212-7050

Funding

Modeling transcriptional and post-transcriptional systems for regulating non-genetic heterogeneity in mammalian cellsR35GM149531 · NIGMS · UNIVERSITY OF TEXAS DALLAS · PI Tian Hong · 2023 to 2026
$1.5M
National Science Foundation 2243562NIGMS NIH HHS R35 GM149531NIH HHS R35GM149531
6 · The paper itself

Abstract

motivationQuantitative analyses of epithelial-mesenchymal transition (EMT) have been widely used in several areas of biomedical sciences due to its importance in development and cancer progression, but its multi-contextual nature requires standardization and implementation of gene set scoring methods beyond capacities of conventional tools.

resultsWe developed EMTscore, a package that provides an efficient implementation of unbiased scoring methods for multiple EMT pathways using individual single-cell or bulk omics data, and the package allows rapid screening for cellular processes correlated with EMT. AVAILABILITY AND IMPLEMENTATION: EMTscore is available from GitHub https://github.com/wenmm/EMTscore under the GNU General Public License, and is uploaded on Zenodo with a DOI 10.5281/zenodo.19487376.

Indexed as

Computational BiologyEpithelial-Mesenchymal TransitionSoftwareGene Expression ProfilingGenomicsHumans

Identifiers

PMID42097304
PMCPMC13186194

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.