Evidence map›Paper›PMID 42097024›Full record

ArticleBiomaterials2026

Chronic alteration of Ca

Naofumi Suematsu, Alberto L Vazquez, Takashi Dy Kozai

Abstract read
In one paragraph

Article in Biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Naofumi SuematsuDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States of America; Department of Molecular Cell Physiology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Alberto L VazquezDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States of America; Center for the Neural Basis of Cognition, University of Pittsburgh and Carnegie Mellon University, Pittsburgh, PA, United States of America; Department of Radiology, University of Pittsburgh, Pittsburgh, PA, United States of America; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, United States of America.
Takashi Dy KozaiDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States of America; Center for the Neural Basis of Cognition, University of Pittsburgh and Carnegie Mellon University, Pittsburgh, PA, United States of America; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, United States of America; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America; Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA, United States of America. Electronic address: tk.kozai@pitt.edu.

Funding

Using Electrical Stimulation to Modulation Microglia and the Conversion of Microglia PhenotypesR01NS115707 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KOZAI, TAKASHI DANIEL YOSHIDA · 2020 to 2024
$3.2M
Subcellular Wireless Axons for in vivo Localized Neuronal ExcitationR01NS105691 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Takashi Daniel Yoshida Kozai, Wen Li · 2020 to 2026
$3.1M
Mechanisms of Oligodendrocyte Activity on Chronic Brain Implants and Recording PerformanceR01NS129632 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FRANCA CAMBI, Takashi Daniel Yoshida Kozai · 2023 to 2026
$2.4M
NINDS NIH HHS R01 NS105691NINDS NIH HHS R01 NS115707NINDS NIH HHS R01 NS129632
6 · The paper itself

Abstract

Understanding the chronic effects of intracortical microstimulation (ICMS) and device implantation on cortical function is essential for the development of stable neuroprosthetics. We chronically implanted penetrating microelectrodes into Thy1-GCaMP6s mice and conducted longitudinal mesoscopic widefield and two-photon Ca

Indexed as

CalciumHemodynamicsVisual CortexWakefulnessAnimalsElectric StimulationMaleMiceMice, Inbred C57BLMicroelectrodesPhotic StimulationCalciumEpileptiform activityMetabolic stressNeuronal silencingSeizure susceptibilitySpatial response mappingVascular remodeling indicatorsVisual prosthesis

Identifiers

PMID42097024
PMCPMC13684390

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.