Evidence map›Paper›PMID 42096709›Full record

ArticleAnnals of medicine2026

The association between weight-adjusted waist circumference index and risks of cardiovascular and all-cause mortality: a retrospective analysis based on the NHANES database.

Wentai Yang, Maoping Wang, Xian Huang, Guoxin He, Tingting Qi, Qing Jin

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Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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3 · Its place in the literature

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1 citing paper in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Wentai YangDepartment of Gastroenterology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.
Maoping WangThe First Clinical Medical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Xian HuangThe First Clinical Medical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Guoxin HeThe First Clinical Medical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Tingting QiThe First Clinical Medical College, Gannan Medical University, Ganzhou, Jiangxi, China.
Qing JinLaboratory Medicine, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNowadays, obesity has become a public health issue. Weight-adjusted waist circumference index (WWI) is gaining attention as a new obesity indicator. Evidence regarding the association between WWI and all-cause mortality and cardiovascular mortality among the general adult population in the United States remains limited.

methodsThis retrospective cohort study analyzed 3,081 U.S. adults from the 1999-2018 NHANES database. Weighted Cox regression, trend chi-square test, Kaplan-Meier analysis, and comprehensive predictive performance assessments were used to explore the association between WWI and all-cause/cardiovascular mortality, and validate WWI's predictive value versus BMI/waist circumference/body weight. Subgroup and interaction analyses were also performed.

resultsWWI was positively associated with all-cause (Model 3 HR = 1.944,

conclusionThis study demonstrates a significant association between WWI and all-cause mortality and cardiovascular mortality among the general adult population in the United States, Our findings suggest that older people, women, low-income and low-educated people, smokers have higher WWI, and people with high WWI also have higher prevalence of hypertension and diabetes, Integrating WWI into clinical risk assessment may help identify high-risk populations and guide targeted interventions to reduce mortality risk.

Indexed as

Cardiovascular DiseasesObesityWaist CircumferenceAdultAgedBody Mass IndexBody WeightCause of DeathFemaleHumansMaleMiddle AgedNutrition SurveysRetrospective StudiesRisk FactorsUnited Statesall-cause mortalitybody mass indexcardiovascular mortalityWeight-adjusted waist circumference index

Identifiers

PMID42096709
PMCPMC13159585

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