Evidence map›Paper›PMID 42096368›Full record

ArticleInternational archives of allergy and immunology2026

Food Protein-Induced Enterocolitis Syndrome among Canadian Children Living in Montreal.

Angela Mulé, Pasquale Mulé, Adnan Al Ali, Catherine Prattico, Xun Zhang, Christine McCusker, Vicky Le Blanc, Moshe Ben-Shoshan

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Article in International archives of allergy and immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Angela MuléDivision of Allergy and Clinical Immunology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Québec, Canada, angelaat.mule@gmail.com.
Pasquale MuléDivision of Allergy and Clinical Immunology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Québec, Canada.
Adnan Al AliDivision of Allergy and Clinical Immunology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Québec, Canada.
Catherine PratticoDivision of Allergy and Clinical Immunology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Québec, Canada.
Xun ZhangDivision of Allergy and Clinical Immunology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Québec, Canada.
Christine McCuskerDivision of Allergy and Clinical Immunology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Québec, Canada.
Vicky Le BlancDivision of Allergy, Department of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Moshe Ben-ShoshanDivision of Allergy and Clinical Immunology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Québec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionData on food protein-induced enterocolitis syndrome (FPIES) are sparse. We aimed to evaluate sociodemographic characteristics, comorbidities, and allergens of children presenting with FPIES. Tolerance to baked goods and resolution a year following diagnosis were also assessed.

methodsChildren with physician-diagnosed FPIES were enrolled and followed at the Montreal Children's Hospital and an affiliated clinic. Families were queried on the food allergen and comorbidities, as well as clinical characteristics of reaction and management.

resultsBetween November 2021 and April 2025, 87 children with a confirmed history of FPIES were enrolled. Patient ages ranged from 1 month to 13 years old, and 45% of patients were males. The most common allergens included egg, shellfish, milk, fish, peanut, oat, fruit, soy/grains, and rice. Symptoms included vomiting, lethargy, pallor, diarrhea, dehydration, and abdominal pain. Tolerance to baked forms was seen in the majority of patients. The allergens that had resolved FPIES include egg, milk, oat, soy/grains, peanut, shellfish. DISCUSSION: The most common food allergens are egg, milk, and shellfish. The majority of reactions are not severe and baked goods containing the culprit food are often tolerated. Resolution of FPIES was reported in most patients 1 year following diagnosis.

Indexed as

Baked food toleranceFood allergensFood protein-induced enterocolitis syndromeSymptom resolution

Identifiers

PMID42096368
PMCPMC13341092

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