Evidence map›Paper›PMID 42096161›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Isolating C. difficile from Animal Samples.

Deiziane V S Costa, Cirle A Warren

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Deiziane V S CostaDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA. dv2t@virginia.edu.
Cirle A WarrenDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clostridioides difficile (C. difficile), which has historically denominated Bacillus difficile, was first isolated by Hall and O'Toole in fecal samples of newborns during the first 10 days of life in 1935. Isolation of C. difficile from animal fecal specimens is critical for understanding the susceptibility and virulence of circulating strains through in vitro and preclinical studies, helping clinicians and researchers understand the different outcomes of CDI in the host associated with the pathogen's virulence. In this chapter, we will describe step-by-step procedures for isolating C. difficile from fecal specimens from animals with a focus on a method using taurocholate Cycloserine-Cefoxitin Fructose Agar (TCCFA) plates preceded by an alcohol shock.

Indexed as

Bacteriological TechniquesClostridioides difficileClostridium InfectionsFecesAnimalsAnti-Bacterial AgentsCulture MediaAnti-Bacterial AgentsCulture MediaAntibiotic selectionBacterial isolationClostridioides difficile

Identifiers

PMID42096161

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.