Evidence map›Paper›PMID 42096156›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Measuring C. difficile Adhesion to Mucosal Surfaces.

Ben S Sidner, Hugh C McCullough, Baishakhi Biswas, Jennifer M Auchtung, Kurt H Piepenbrink

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ben S SidnerDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE, USA.
Hugh C McCulloughDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE, USA.
Baishakhi BiswasDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE, USA.
Jennifer M AuchtungDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE, USA.
Kurt H PiepenbrinkDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE, USA. kurt.piepenbrink@unl.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colonization of the host gastrointestinal tract by Clostridioides difficile requires attachment to host tissues which is likely an integrative process potentially involving multiple modes of attachment, host cells, extracellular structures, and bacterial aggregation. Attachment to host mucosa represents a novel mechanism for understanding C. difficile's persistence, either during infection or asymptomatic colonization. In this chapter, we describe methods for directly measuring the in vitro attachment of C. difficile to mucin hydrogels from a variety of sources.

Indexed as

Bacterial AdhesionClostridioides difficileIntestinal MucosaMucous MembraneAnimalsHost-Pathogen InteractionsHumansHydrogelsMucinsHydrogelsMucinsAdhesionGlycobiologyHost-pathogen interactionsMucin

Identifiers

PMID42096156

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.