Evidence map›Paper›PMID 42096155›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

In Vitro Measurement of Clostridioides difficile Biofilm Formation Induced by Gut and Microbiota-Derived Signals.

Carolina Altaf Figueiredo, Bruno Dupuy

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Carolina Altaf FigueiredoInstitut Pasteur, Université Paris-Cité, UMR-CNRS 6047, Laboratoire Pathogenèse des Bactéries Anaérobies, Paris, France. carolina.altaf-figueiredo@pasteur.fr.
Bruno DupuyInstitut Pasteur, Université Paris-Cité, UMR-CNRS 6047, Laboratoire Pathogenèse des Bactéries Anaérobies, Paris, France. bruno.dupuy@pasteur.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studying biofilm formation in liquid cultures is a rapid and straightforward method for identifying relevant experimental and bacterial factors before conducting tests in more complex gut models. Recent studies showed that several recurrent pathogenic bacteria form biofilms in response to host and microbiota-derived signals. Clostridioides difficile biofilms present as heterogeneous structures are highly dependent on strain, environmental signals, and surrounding microbes. Here, we describe protocols for studying induced C. difficile biofilm formation in the function of gut-derived factors.

Indexed as

BiofilmsClostridioides difficileGastrointestinal MicrobiomeBile Acids and SaltsHumansMicrobiotaBile Acids and SaltsBile acidsBiofilmMicrobiota

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.