Evidence map›Paper›PMID 42096131›Full record

ArticleEuropean radiology experimental2026

Combining DMI and [

Viktoria Ehret, Usevalad Ustsinau, Clemens Fürnsinn, Thomas Scherer, Jana Starčuková, Marcus Hacker, Martin Krššák, Cécile Philippe

Abstract read
In one paragraph

Article in European radiology experimental, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Viktoria Ehret *Department of Medicine III, Division of Endocrinology and Metabolism, Medical University of Vienna, Vienna, Austria.
Usevalad Ustsinau *Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.
Clemens FürnsinnDepartment of Medicine III, Division of Endocrinology and Metabolism, Medical University of Vienna, Vienna, Austria.
Thomas SchererDepartment of Medicine III, Division of Endocrinology and Metabolism, Medical University of Vienna, Vienna, Austria.
Jana StarčukováInstitute of Scientific Instruments, Czech Academy of Sciences, Brno, Czech Republic.
Marcus HackerDepartment of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria.
Martin KrššákDepartment of Medicine III, Division of Endocrinology and Metabolism, Medical University of Vienna, Vienna, Austria.
Cécile PhilippeDepartment of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria. cecile.philippe@meduniwien.ac.at.ORCID http://orcid.org/0000-0002-7203-7174

Funding

Vienna Science and Technology Fund 10.47379/LS19046
6 · The paper itself

Abstract

The unique capability of deuterium metabolic imaging (DMI) to detect downstream metabolic products and trace substrates' transport within tissues using conventional magnetic resonance (MR) scanners can, in theory, be employed with routine positron emission tomography (PET)/MR equipment. Our technical proof-of-concept study proposes a protocol for the simultaneous acquisition of DMI and [¹⁸F]FDG-PET data to enable dual assessment of hepatic glucose metabolism. A protocol that integrates high-dose glucose administration, required for DMI, with [¹⁸F]FDG-PET imaging was applied in a spectroscopy-validated rodent model of metabolic dysfunction-associated fatty liver disease (MAFLD). We acquired and quantified high-quality DMI and PET data of the liver that could provide a distinction between healthy and MAFLD cohorts in the future. RELEVANCE STATEMENT: This proof-of-concept study demonstrates the simultaneous DMI-[

Indexed as

DeuteriumFatty LiverFluorodeoxyglucose F18Positron-Emission TomographyAnimalsDisease Models, AnimalGlucoseLiverMagnetic Resonance ImagingRadiopharmaceuticalsRatsDeuteriumFluorodeoxyglucose F18GlucoseRadiopharmaceuticalsDeuteriumGlucose metabolism disordersMagnetic resonance spectroscopyNon-alcoholic fatty liver diseasePositron emission tomography

Identifiers

PMID42096131
PMCPMC13153327

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.