ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2026
Peak frequency annotation algorithm-guided slow pathway ablation enables lesion delivery farther from the His bundle in typical atrioventricular nodal reentrant tachycardia.
Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough slow pathway ablation is an established curative therapy for typical atrioventricular nodal reentrant tachycardia (AVNRT), lesion delivery is constrained by the anatomical proximity to the His bundle, limiting the procedural safety margin. Peak frequency mapping (PFM) is a novel physiology-based method that highlights regions of the slow pathway-related electrograms and may enable safer ablation at more annular sites.
objectiveTo evaluate the reproducibility, procedural safety, and clinical efficacy of PFM-guided slow pathway ablation compared with the conventional anatomical approach.
methodsEighty-one consecutive patients with typical AVNRT were analyzed (39 conventional, 42 PFM-guided). Procedural characteristics, acute success, safety outcomes, and mid-term recurrence were assessed.
resultsPFM consistently localized the slow pathway around the 4-5 o'clock region of the tricuspid annulus and enabled effective ablation at significantly greater distances from the His bundle (22.8 ± 5.5 vs. 11.5 ± 3.2 mm, p < 0.0001). Acute success was achieved in all PFM-guided cases and in 97.4% of conventional cases. PFM-guided ablation required fewer RF applications and demonstrated earlier and slower junctional rhythm during energy delivery. During a mean follow-up of 822 ± 362 days, recurrence occurred in 2 conventional patients (5.1%) but in none of the PFM-guided patients.
conclusionsPFM-guided slow pathway ablation enables lesion delivery at annular sites farther from the His bundle while maintaining acute success and mid-term efficacy. By facilitating ablation at sites more distant from the His bundle, this physiology-based strategy may provide a wider procedural safety margin and represents a reproducible refinement of conventional AVNRT ablation.
Indexed as
Identifiers
42095983What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.