Evidence map›Paper›PMID 42095890›Full record

ReviewPharmaceutical biology2026

Medicinal food plants of Sabah (Eastern Malaysia): a source of potential natural products and nutraceuticals for the fight against cancer.

Carynn Tanbuda, Mazdida Sulaiman, Pauline Yong Pau Lin, Fiffy Hasnidah Saikim, Nor Azizun Ruzdi, Mogana Rajagopal, Nicholas Pang Tze Ping, Nor Hayati Abdullah, Jhonnel Villegas, Sanen Marshall and 6 more

Abstract readReview
In one paragraph

Review in Pharmaceutical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Carynn TanbudaInstitute for Tropical Biology and Conservation, Universiti Malaysia Sabah, jalan UMS, Kota Kinabalu, Sabah, Malaysia.
Mazdida SulaimanDepartment of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur, Malaysia.
Pauline Yong Pau LinFaculty of Social Sciences and Humanities, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu, Sabah, Malaysia.
Fiffy Hasnidah SaikimInstitute for Tropical Biology and Conservation, Universiti Malaysia Sabah, jalan UMS, Kota Kinabalu, Sabah, Malaysia.
Nor Azizun RuzdiInstitute for Tropical Biology and Conservation, Universiti Malaysia Sabah, jalan UMS, Kota Kinabalu, Sabah, Malaysia.
Mogana RajagopalFaculty of Pharmaceutical Sciences, UCSI University, Cheras, Kuala Lumpur, Malaysia.
Nicholas Pang Tze PingFaculty of Medicine, Universiti Malaysia Sabah, jalan UMS, Kota Kinabalu, Sabah, Malaysia.
Nor Hayati AbdullahNatural Product Division, Forest Research Institute of Malaysia, Kepong, Kuala Lumpur, Malaysia.
Jhonnel VillegasFaculty of Teacher Education, Davao Oriental State University, Davao Oriental, Philippines.
Sanen MarshallCenter for the Promotion of Knowledge and Language Learning, Universiti Malaysia Sabah, jalan UMS, Kota Kinabalu, Sabah, Malaysia.
Mukesh Singh SikarwarAmity Institute of Pharmacy, Amity University, Gwalior, Madhya Pradesh, India.
Veeranoot NissapatornFuturistic Science Research Center (FSRC) - School of Science, Research Excellence Center for Innovation and Health Products (RECIHP) and World Union for Herbal Drug Discovery (WUHeDD), Walailak University, Nakhon Si Thammarat, Thailand.
Prapairat SeephonkaiDepartment of Chemistry, Faculty of Science, Mahasarakham University, Maha Sarakham, Thailand.
Marcelo IritiDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Mark S ButlerMSBChem Consulting, Brisbane, QLD, Australia.
Christophe WiartDepartment of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextThe pharmaceutical and nutraceutical industries are seeking structurally and pharmacologically novel anticancer molecules, as well as onco-protective nutraceuticals. One approach to achieving this goal is to study traditional pharmacopoeias, particularly those from regions where cancers are less common. Certain ethnic groups in Sabah (East Malaysia) appear to have a low incidence of cancer, and the study of their pharmacopeia could lead to the discovery of original anticancer molecules or nutraceuticals.

objectivesThis review presents a selection of 64 plants used for medicinal food in Sabah their potential for clinical uses.

methodsThe data for this focused narrative review were gathered from Google Scholar, PubMed, ScienceDirect, Web of Science, PubMed, the Internet Archive, and Google books. For each plant the search string included the binomial denomination and the words "cytotoxic" or "tumors." of the binomial denomination of each plant and "cytotoxic" and "tumors" was employed. Each result was examined and articles that did not contain information relevant to the topic or coming from non-peer-reviewed journals were excluded.

resultsEight plant species, of which

conclusionThere is currently a need to find oncopreventive nutraceuticals as well as original natural products for developing anticancer drugs. Such products could potentially be found among the medicinal and edible plants of Sabah. Further studies are needed.

Indexed as

Antineoplastic Agents, PhytogenicBiological ProductsDietary SupplementsNeoplasmsPlant ExtractsPlants, MedicinalAnimalsHumansMalaysiaPhytotherapyAntineoplastic Agents, PhytogenicBiological ProductsPlant ExtractsBorneoethnopharmacologynatural productsoncology

Identifiers

PMID42095890
PMCPMC13159609

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.