Evidence map›Paper›PMID 42095869›Full record

ArticlePsychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors2026

Adolescent music engagement is associated with less alcohol consumption and substance experimentation 5-11 years later: A genetically informative study.

Lydia Rader, Hermine H M Maes, Naomi P Friedman, Reyna L Gordon, Miriam D Lense, Michael C Stallings, Chandra A Reynolds, Daniel E Gustavson

Abstract read
In one paragraph

Article in Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Lydia RaderInstitute for Behavioral Genetics, University of Colorado Boulder.ORCID 0000-0002-2290-7653
Hermine H M MaesVirginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University.
Naomi P FriedmanInstitute for Behavioral Genetics, University of Colorado Boulder.
Reyna L GordonDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center.
Miriam D LenseDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center.
Michael C StallingsInstitute for Behavioral Genetics, University of Colorado Boulder.
Chandra A ReynoldsInstitute for Behavioral Genetics, University of Colorado Boulder.
Daniel E GustavsonInstitute for Behavioral Genetics, University of Colorado Boulder.

Funding

Twin StudyP60DA011015 · NIDA · UNIVERSITY OF COLORADO DENVER · PI HEWITT, JOHN K. · 1997 to 2013
$22.5M
Establishing if Music Engagement is a Protective Factor in Adolescent Substance Use Using Existing Longitudinal, Genetic, and Environmental DatasetsR01DA059804 · NIDA · UNIVERSITY OF COLORADO · PI Daniel Gustavson · 2024 to 2026
$2.0M
Vulnerability to Substance Use: Transitions and Trajectories in ABCD Youth with Validation Using Longitudinal Twin Family SamplesR01DA063061 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI Naomi P. Friedman, Monica Luciana · 2025 to 2026
$1.4M
Implications of midlife alcohol use for risk of dementia in male and female twins: Unique contributions and interactions with APOE4R21AG087486 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LUCZAK, SUSAN E · 2024 to 2024
$469k
NIA NIH HHS R21 AG087486NIDA NIH HHS P60 DA011015NIDA NIH HHS R01 DA059804NIDA NIH HHS R01 DA063061Office of Behavioral and Social Sciences Research
6 · The paper itself

Abstract

objectiveAdolescence is a critical developmental window for shaping substance use trajectories. Music engagement during this period may reduce substance experimentation and later misuse through direct effects or shared etiological influences, and these associations may differ by genetic risk.

methodUsing a genetically informed, longitudinal design, we analyzed associations between music engagement at Age 12 and substance use outcomes at Ages 17 and 23 in the Colorado Longitudinal Twin sample (413 same-sex twin pairs; 50% female; 91.9% White; 9.1% Hispanic). Music engagement and substance use were assessed using questionnaires developed for this study. Twin modeling was used to disentangle causal from etiological influences, and polygenic scores were used to test whether associations are strongest for those at highest genetic risk.

resultsMusic engagement was associated with less alcohol use and substance experimentation across adolescence and young adulthood (

conclusionsMusic engagement is associated with reduced substance use in adolescence and young adulthood, driven by protective shared environmental influences rather than direct effects. Music engagement may represent a constructive environmental outlet for youth, underscoring the importance of genetically informed research. However, the results may not generalize to more contemporary and/or diverse cohorts. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Identifiers

PMID42095869
PMCPMC13155363

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.