Evidence map›Paper›PMID 42095546›Full record

ArticleeLife2026

Prolonged oscillating preoptic area kisspeptin neuron activity underlies the preovulatory luteinizing hormone surge in mice.

Ziyue Zhou, Cheng-Yu Huang, Allan Edward Herbison

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ziyue ZhouDepartment of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.
Cheng-Yu HuangDepartment of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0002-2153-4584
Allan Edward HerbisonDepartment of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0002-9615-3022

Funding

Harding Distinguished Postgraduate Scholars Programme Leverage SchemeMedical Research Council N013433-1UKRI Medical Research Council Equipment MC-PC-MR-X012271/1Wellcome Trust 10.35802/212242
6 · The paper itself

Abstract

The population of kisspeptin neurons located in the rostral periventricular area of the third ventricle (RP3V) is thought to have a key role in generating the GnRH surge that triggers ovulation. Using a modified GCaMP fibre photometry procedure, we have been able to record the in vivo population activity of RP3V

Indexed as

KisspeptinsLuteinizing HormoneNeuronsPreoptic AreaAnimalsEstradiolEstrous CycleFemaleHypothalamic-Pituitary-Gonadal AxisMiceOvariectomyOvulationThird VentricleEstradiolKisspeptinsLuteinizing HormoneestrogenGnRHkisspeptinLH surgemouseneurosciencephotometry

Identifiers

PMID42095546
PMCPMC13152274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.