Evidence map›Paper›PMID 42095449›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

H

Shuang Liang, Meng-Hao Li, Liang Cheng, Tian-Shou Zhang, Hui Hui, Yan Wang, Hong-Pu Zhang, Bo-Wen Liu, Lin Wang, Ying-Wei Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Porphyrin-Based Porous Materials for Antibacterial Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shuang LiangDepartment of Prosthodontics, Jilin Provincial Key Laboratory of Sciences and Technology for Stomatology Nanoengineering, School and Hospital of Stomatology, Jilin University, Changchun, P. R. China.
Meng-Hao LiCollege of Chemistry, Jilin University, Changchun, P. R. China.
Liang ChengDepartment of Prosthodontics, Jilin Provincial Key Laboratory of Sciences and Technology for Stomatology Nanoengineering, School and Hospital of Stomatology, Jilin University, Changchun, P. R. China.
Tian-Shou ZhangDepartment of Prosthodontics, Jilin Provincial Key Laboratory of Sciences and Technology for Stomatology Nanoengineering, School and Hospital of Stomatology, Jilin University, Changchun, P. R. China.
Hui HuiCollege of Chemistry, Jilin University, Changchun, P. R. China.
Yan WangCollege of Chemistry, Jilin University, Changchun, P. R. China.
Hong-Pu ZhangDepartment of Prosthodontics, Jilin Provincial Key Laboratory of Sciences and Technology for Stomatology Nanoengineering, School and Hospital of Stomatology, Jilin University, Changchun, P. R. China.
Bo-Wen LiuDepartment of Prosthodontics, Jilin Provincial Key Laboratory of Sciences and Technology for Stomatology Nanoengineering, School and Hospital of Stomatology, Jilin University, Changchun, P. R. China.
Lin WangDepartment of Prosthodontics, Jilin Provincial Key Laboratory of Sciences and Technology for Stomatology Nanoengineering, School and Hospital of Stomatology, Jilin University, Changchun, P. R. China.ORCID https://orcid.org/0000-0002-5696-1076
Ying-Wei YangCollege of Chemistry, Jilin University, Changchun, P. R. China.

Funding

Interdisciplinary Innovation Team Project of Norman Bethune Health Science Department, Jilin University 2025JBGS04Jilin Provincial Science and Technology Department's Young Talent Training Program 20250602067RCNational Natural Science Foundation of China 22571119National Natural Science Foundation of China 82170998National Natural Science Foundation of China 82571148Science and Technology Project of Jilin Province Financial Department -11Science and Technology Project of Jilin Province Financial Department JCSZ2025678-4
6 · The paper itself

Abstract

Reactive oxygen species (ROS)-based nanomedicine holds great promise for combating biofilm-associated infections (BAIs). Nonetheless, the strong antioxidant systems in these microenvironments lessen the effectiveness of ROS. The combination of ROS generation and depletion of antioxidant pathways is a potential approach to this issue. Herein, we present COF/HKUST-10, a composite platform of a copper-based metal-organic framework (HKUST-1) and pillararene-embedded covalent organic frameworks for BAIs. Both endogenous hydrogen sulfide and exogenous light activate this platform, thereby inducing synergistic catalytic reactions that enhance ROS generation and local antioxidant inhibition. Transcriptomic analysis revealed that ROS and Cu

Indexed as

Anti-Bacterial AgentsHydrogen SulfidePeriodontitisAntioxidantsBiofilmsCopperHumansPorphyromonas gingivalisReactive Oxygen SpeciesAnti-Bacterial AgentsAntioxidantsCopperHydrogen SulfideReactive Oxygen Speciesbiofilm‐associated infectionscovalent organic frameworksmultifunctional combination therapyperiodontitispillararene

Identifiers

PMID42095449
PMCPMC13335815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.