Evidence map›Paper›PMID 42095293›Full record

ArticlePain research & management2026

Do White Noise or Music Relieve Pain Caused by Botulinum Toxin Injections?

Zuleyha Ozgen

Abstract read
In one paragraph

Article in Pain research & management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Zuleyha OzgenDepartment of Dermatology, Acibadem Hospital, Atasehir, Istanbul, Turkey, acibadem.com.tr.ORCID https://orcid.org/0000-0002-9377-9548

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the impact of music and white noise on the pain caused by cosmetic botulinum toxin injections. PATIENT AND

methodSeventy-six participants between the ages of 18 and 45 who requested cosmetic botulinum toxin application to the upper face were enrolled in the study in three groups: favorite music (20), white noise (31), and control (25). The first and second groups listened to their favorite music and white noise, respectively, during and 10 min after the procedures, while the control group was exposed to background noise only. The participants rated their pain levels during the procedure and the impact of the sound on their stress level using a visual analog scale ranging from 0 to 10. Additionally, the participants in both the music and white noise groups were surveyed regarding their preferences for sound intervention for future botulinum toxin procedures.

resultThe pain scores (95% confidence interval) for the control, music, and white noise groups were 6.80 [6.37-7.23], 5.7 [5.13-6.27], and 5.52 [4.99-6.04], respectively. Both the white noise group and the music group had significantly lower pain scores compared to the control group. Furthermore, individuals receiving botulinum toxin for the first time reported significantly higher pain scores than those who had prior experience with the treatment.

conclusionListening to white noise or music during cosmetic botulinum toxin injections can effectively reduce procedure-related pain. However, further studies are required to reveal the mechanism of action of sound applications in pain management during cosmetic procedures and to determine the selection of appropriate candidates and specific application conditions.

Indexed as

Botulinum ToxinsMusicMusic TherapyNoisePainPain ManagementAdolescentAdultFemaleHumansMaleMiddle AgedPain MeasurementYoung AdultBotulinum Toxinsbotulinum toxinmusicpainwhite noise

Identifiers

PMID42095293
PMCPMC13150686

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.