Evidence map›Paper›PMID 42095207›Full record

ArticleJournal of bone oncology2026

CDK4/6 inhibitor ribociclib and doxorubicin combination treatment inhibits breast cancer bone metastasis and enhances T-cell targeted therapy.

Xinming Su, Takayuki Kobayashi, Jingyu Xiang, Yalin Xu, Ayesha N Shajahan-Haq, Mahta Mardani, Suleyman Noordeen, Kaylee O'Donnell, Kristin A Kwakwa, Dennis Guan and 9 more

Abstract read
In one paragraph

Article in Journal of bone oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Xinming SuDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Takayuki KobayashiDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Jingyu XiangDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Yalin XuDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Ayesha N Shajahan-HaqDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.
Mahta MardaniDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Suleyman NoordeenDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Kaylee O'DonnellDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Kristin A KwakwaDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Dennis GuanDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Gregory C FoxDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Francesca FontanaDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Emily CybullaDepartment of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH 43210, USA.
Suzanne BakewellDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Alessandro VindigniDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Deborah J VeisDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Samuel AchilefuSiteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
Gregory M LanzaDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Katherine N WeilbaecherDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CDK4/6 inhibitors (CDK4/6i) combined with endocrine therapy, specifically aromatase inhibitors or selective estrogen receptor degraders or modulators, have significantly improved outcomes for advanced estrogen receptor-positive (ER

Identifiers

PMID42095207
PMCPMC13139965

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.