Evidence map›Paper›PMID 42095070›Full record

ArticleiScience2026

GUTK induces apoptosis in reactivating quiescent prostate cancer cells

Yalin Wang, Yang Li, Xue Jiang, Xiaoqiong Chen, Mengfan Liu, Hangui Ren, Yulong Zhang, Rongchen Dai, Zhichao Xi, Hongxi Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yalin WangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Yang LiSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Xue JiangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Xiaoqiong ChenSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Mengfan LiuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Hangui RenSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Yulong ZhangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Rongchen DaiSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Zhichao XiSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Hongxi XuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quiescent prostate cancer (PCa) cells that survive therapy can later reactivate and drive tumor recurrence and metastasis. Here, we identify a strategy to eliminate these cells during their vulnerable reactivation phase. We show that guttiferone K (GUTK), a bioactive compound isolated from

Indexed as

biochemistrycancerpharmacology

Identifiers

PMID42095070
PMCPMC13141025

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.