ReviewGynecologic oncology reports2026
Risk of venous thromboembolism following human papillomavirus vaccination: a systematic review and meta-analysis.
Review in Gynecologic oncology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
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Abstract
Background: Sporadic reports linking human papillomavirus (HPV) vaccination to venous thromboembolism (VTE) have raised safety concerns. We intended to provide an updated and comprehensive evaluation of this potential association using recent large-scale data. Methods: We conducted a systematic review and Results: Eight observational studies involving millions of participants were included. The pooled analysis showed no statistically significant association between HPV vaccination and VTE risk (Risk Ratio = 0.87; 95%CI: 0.71-1.07; P = 0.183). Consistency was observed across all subgroups, including age (<18 vs. ≥18 years), sex (female vs. male), and vaccine valency (including 9-valent). Conclusion: Current evidence indicates that HPV vaccination is not associated with an increased risk of VTE. These findings reinforce the favorable safety profile of HPV vaccines across diverse populations and support continued vaccination programs.
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