Evidence map›Paper›PMID 42094992›Full record

ArticleASM case reports2026

Two case reports on the identification and management of hypervirulent

John S Stevenson, Emily D Dyer, Paul D Fey, Trevor C Van Schooneveld, Michael R Wiley, Peter C Iwen, Ulrike Carlino-MacDonald, Thomas A Russo

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in ASM case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

John S Stevenson *Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, USA.ORCID https://orcid.org/0009-0005-5631-5794
Emily D Dyer *Division of Infectious Disease, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Paul D FeyDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, USA.ORCID https://orcid.org/0000-0003-0939-6884
Trevor C Van SchooneveldDivision of Infectious Disease, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Michael R WileyDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Peter C IwenDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Ulrike Carlino-MacDonaldVeterans Administration Western New York Healthcare System, Buffalo, New York, USA.
Thomas A RussoVeterans Administration Western New York Healthcare System, Buffalo, New York, USA.ORCID https://orcid.org/0000-0003-4566-7442

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hypervirulent Case Summary: Two patients from Nebraska presented with complex abscesses of unknown origin. Both cases required interventional procedures and prolonged hospitalization. PCR-based testing, animal studies, and whole-genome sequencing analysis confirmed that hvKp was the offending pathotype. Conclusion: This report describes the first confirmed cases of hvKp infection in Nebraska, USA. These cases demonstrated the utility of using molecular methods to identify hvKp. The microbiology lab can be operationalized to provide valuable insights into the genetic makeup of pathogens, inform the institutional clinical decision-making processes, and epidemiological surveillance. This study highlights the collaborative relationships between the Infectious Diseases staff and the Clinical Microbiology Laboratory to work up complex cases.

Indexed as

clinical microbiologyemerging pathogenhypervirulent Klebsiella pneumoniaemolecular diagnostics

Identifiers

PMID42094992
PMCPMC13141873

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.