ArticleFrontiers in medicine2026
Radiotherapy combined with DEB-BACE for locally advanced lung cancer with obstructive atelectasis following first-line treatment failure: case report.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
For patients with locally advanced non-small cell lung cancer (NSCLC) who are intolerant to concurrent chemoradiotherapy, sequential chemotherapy followed by radiotherapy is a standard alternative treatment. However, disease progression after first-line chemotherapy results in poor prognosis, and radiotherapy alone often fails to achieve ideal tumor control. Notably, these patients exhibit a higher incidence of obstructive atelectasis, which further worsens clinical outcomes. This study reports two unique cases of locally advanced NSCLC with obstructive atelectasis after first-line chemotherapy failure. Both patients received combined therapy with radiotherapy and drug-eluting bead bronchial artery chemoembolization (DEB-BACE). Results demonstrated preliminary control of atelectasis in both patients, followed by long-term remission post-treatment. These findings suggest that radiotherapy combined with DEB-BACE may be a promising potential strategy for locally advanced NSCLC patients accompanied by atelectasis.
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