ArticleEnvironmental research, health : ERH2026
Polycyclic aromatic hydrocarbons (PAHs) contribute to inflammation in a pregnancy cohort.
Article in Environmental research, health : ERH, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants generated from incomplete combustion and are detectable in nearly all individuals in the U.S. population. Prenatal PAH exposure has been linked to adverse birth and child health outcomes, but few studies have examined associations between biomarkers of PAHs and inflammation during pregnancy across gestational windows. We investigated associations between urinary PAH metabolites and urinary inflammatory markers among 159 pregnant women enrolled in the placental assessment in response to environmental exposures cohort (2016-2019). Urine samples were collected up to three times during pregnancy (10-17, 18-29, and ⩾30 gestational weeks). Hydroxylated PAHs metabolites were quantified using liquid chromatography-tandem mass spectrometry, and inflammatory markers (IL-6, IL-1
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