Evidence map›Paper›PMID 42094916›Full record

ReviewBrain & spine2026

Evaluation of bony fusion after posterior lumbar interbody fusion: a systematic review and meta-analysis.

Luc W F van Haaster, Rania A Mekary, Carmen L A Vleggeert-Lankamp

Abstract readReview
In one paragraph

Review in Brain & spine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Luc W F van HaasterDepartment of Neurosurgery, Leiden University Medical Center, Leiden, Albinusdreef 2, Leiden, 2333 ZA, the Netherlands.
Rania A MekaryDepartment of Pharmaceutical Business and Administrative Sciences, School of Pharmacy, MCPHS University, 179, Longwood Ave, Boston, MA, 02115, United States of America.
Carmen L A Vleggeert-LankampDepartment of Neurosurgery, Leiden University Medical Center, Leiden, Albinusdreef 2, Leiden, 2333 ZA, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Posterior lumbar interbody fusion (PLIF) is a common surgical procedure for degenerative lumbar conditions, aiming to decompress neural tissue and stabilize the spine. Bony fusion is essential for long-term success, but inconsistent radiological criteria lead to variable reported fusion rates. This systematic review and meta-analysis evaluated quantitative criteria for assessing bony fusion and their impact on fusion rates over time. Research question: What quantitative criteria are used to assess bony fusion after PLIF, and how do these criteria affect fusion rates at different postoperative time points? Material and methods: PubMed, MEDLINE, Embase, Web of Science, Cochrane Library, and CINAHL were searched through November 6, 2025, for studies assessing bony fusion after PLIF using quantitative criteria on dynamic X-ray or CT. Pooled fusion rates were calculated at different postoperative time points, including additional analyses for cage material, smoking, and segmental motion cut-offs. Results: Seventeen studies including 1390 patients were analyzed. Fusion was assessed quantitatively exclusively by dynamic X-ray. Pooled fusion rates increased over time: 76.0% at 6 months, 86.4% at 12 months, 90.2% at 24 months, and 93.4% at 48 months. Optimal cut-off values for segmental motion of ≤3° and ≤4° were chosen due to similar heterogeneity, which was the lowest at 24 months. Discussion and conclusion: Fusion rates reach approximately 90% 24 months after PLIF and show minimal increase thereafter. Evaluating segmental motion with a ≤3°- or ≤4° cut-off provides the most reliable assessment of bony fusion.

Indexed as

Bony fusionDynamic X-rayFusion rateLumbar spinePosterior lumbar interbody fusion

Identifiers

PMID42094916
PMCPMC13142034

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.