ArticleClinical, cosmetic and investigational dermatology2026
Dendrobium and Orchidaceae Plants in Dermatology: A PubMed-Based Bibliometric Analysis and Mechanistic Overview.
Article in Clinical, cosmetic and investigational dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Dendrobium ("Shihu") and other Orchidaceae plants have been investigated as adjunctive options for inflammatory dermatoses, wound repair, and topical skin care. However, clinically relevant evidence and safety information remain scattered across phytochemistry, experimental dermatology, biomaterials, and formulation science. This study used bibliometric methods to map publication patterns and identify themes most closely related to dermatologic mechanisms and safety reporting. Methods: PubMed was searched on January 19, 2026 using a reproducible query that combined Orchidaceae/Dendrobium terms with dermatology and clinical/safety concepts. Records indexed from January 1, 2006 to January 19, 2026 were exported in MEDLINE format and analyzed in R with bibliometrix (v4.3.0) to summarize annual output, contributions by countries and institutions, collaboration networks, source journals, author productivity, and term co-occurrence with burst detection. Results: The final dataset contained 103 records. Annual output increased over time and peaked in 2025 (n=24). China contributed the largest share of publications and occupied a central position in international co-authorship networks. The literature was distributed across 64 journals and covered constituent characterization, experimental models, and delivery/materials-oriented studies. Recent term evolution highlighted growing attention to oxidative stress, signal transduction, and wound repair, whereas safety-related terminology appeared less frequently. Conclusion: Research on Orchidaceae-derived constituents relevant to dermatology is expanding, but clinically oriented evidence remains limited and reporting is heterogeneous, particularly with respect to botanical authentication, extract/formulation characterization, clinically interpretable endpoints, and adverse-event documentation. Better clinical translation will require transparent composition reporting and prospective studies that combine mechanism-linked biomarkers with systematic safety assessment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.