Evidence map›Paper›PMID 42094765›Full record

SynthesisFrontiers in microbiology2026

Bibliometric analysis of genetically engineered bacteria in tumor therapy.

Yanmei Zhu, Yilin Yin, Yaqi Li, Qinghua Wang, Yu Chen, Ke Gu, Rui Yang, Min Zhou, Daozhen Chen

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yanmei Zhu *Wuxi Maternity and Child Health Care Hospital, Jiangnan University, Wuxi, Jiangsu, China.
Yilin Yin *Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China.
Yaqi Li *Wuxi Maternity and Child Health Care Hospital, Jiangnan University, Wuxi, Jiangsu, China.
Qinghua WangWuxi Maternity and Child Health Care Hospital, Jiangnan University, Wuxi, Jiangsu, China.
Yu ChenWuxi Maternity and Child Health Care Hospital, Jiangnan University, Wuxi, Jiangsu, China.
Ke GuDepartment of Radiotherapy, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Rui YangWuxi Maternity and Child Health Care Hospital, Jiangnan University, Wuxi, Jiangsu, China.
Min ZhouDepartment of Breast Surgery, Wuxi Maternity and Child Health Care Hospital, Jiangnan University, Wuxi, Jiangsu, China.
Daozhen ChenWuxi Maternity and Child Health Care Hospital, Jiangnan University, Wuxi, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The utilization of bacteria for tumor treatment has a long-standing history. In recent years, with the continuous advancement of genetic engineering technologies, genetically engineered bacteria have attracted widespread attention in tumor-related research; however, to date, no bibliometric analysis has been reported for this field. In this study, bibliometric methods were employed to comprehensively evaluate the current research status, hotspots, and development trends of genetically engineered bacteria in the tumor field. Studies focusing on genetically engineered bacteria and tumors were retrieved from the Web of Science Core Collection (WOSCC) database and the Scopus database, and bibliometric and visualization analyses were conducted using R, VOSviewer, Scimago Graphica, and CiteSpace. Finally, we discuss the current limitations and challenges associated with the application of genetically engineered bacteria in the tumor field. Future research should focus on improving the safety, targeting capability, and clinical feasibility of engineered bacteria, as well as systematically investigating the interaction mechanisms among different therapeutic modalities, in order to promote the clinical translation of genetically engineered bacteria for tumor treatment.

Indexed as

bacterial therapybibliometricsgene editinggenetically engineered bacteriatumor

Identifiers

PMID42094765
PMCPMC13141310

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.