ArticleFrontiers in microbiology2026
Sea buckthorn seed oil triggers mitochondrial dysfunction and apoptosis in
Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Fungal infections, in particular those caused by Methods: We employed an integrated approach combining network pharmacology, transcriptomics, molecular docking, molecular dynamics (MD) simulations, and experimental validation to systematically investigate the antifungal mechanism of SBT oil against Results: Network pharmacology identified seven key bioactive compounds and 26 potential targets, with enrichment analysis highlighting the advanced glycation end-products (AGE)-receptor for AGEs (RAGE) signaling pathway as a crucial mechanism. Subsequent transcriptomic and experimental validation in Conclusion: This study provides strong evidence that SBT seed oil exerts its antifungal effects against
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