Trial reportNature and science of sleep2026
Effectiveness and Safety of Electroacupuncture in Patients with Treatment-Resistant Insomnia: A Randomized, Assessor-Blinded, Waitlist-Controlled Pilot Trial.
Trial report in Nature and science of sleep, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study evaluated the effectiveness and safety of electroacupuncture in patients with treatment-resistant insomnia (TRI) who experienced persistent sleep disturbances despite using medication for more than 3 months. Patients and Methods: Fifty patients with TRI were randomly assigned to the experimental or waitlist control group. The experimental group received treatment twice a week for 6 weeks. Sleep parameters including the Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), sleep diary, and actigraphy, sleep-related symptoms, quality of life, and costs were evaluated. Results: ISI scores significantly decreased in the experimental group from 2 weeks after treatment initiation, with improvements persisting through the post-treatment and the 4-week follow-up (p < 0.02). After 4 weeks, more patients achieved the minimal clinically important difference for the ISI (p = 0.02). PSQI scores differed significantly between groups at follow-up (p = 0.01). Sleep diary analysis revealed improved morning refreshment from 2 weeks after treatment initiation through follow-up (p < 0.02), with a decrease in sleep onset latency of 12-14 min. In contrast, actigraphy-based sleep parameters showed no significant differences between the groups. After two treatment sessions, ISI scores and moderate-to-severe accompanying symptoms improved. EuroQoL visual analogue scale and SF-36 scores also improved significantly (p = 0.002 and p = 0.007, respectively). Adverse events were similar between groups. Conclusion: Electroacupuncture was associated with improvements in subjective sleep parameters but not in objective actigraphy-based sleep measures in patients with TRI, suggesting that electroacupuncture may be a potential complementary treatment option for patients with insomnia unresponsive to conventional pharmacotherapy.
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