Evidence map›Paper›PMID 42094566›Full record

ArticlebioRxiv : the preprint server for biology2026

Linking human brain functional connectivity to underlying neurotransmission.

Leon D Lotter, Golia Shafiei, Daouia Larabi, Abhay Koushik, Ottavia Dipasquale, Mitul Mehta, Mara Cercignani, Arjun Sethi, Neil Harrison, Štefan Holiga and 12 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Leon D LotterInstitute of Neuroscience and Medicine (INM-7: Brain and Behaviour), Research Centre Jülich; Jülich, Germany.ORCID 0000-0002-2337-6073
Golia ShafieiPenn Lifespan Informatics and Neuroimaging Center (PennLINC), Perelman School of Medicine, University of Pennsylvania; Philadelphia, PA, 19104, USA.ORCID 0000-0002-2036-5571
Daouia LarabiDepartment of Clinical and Developmental Neuropsychology, University of Groningen; Groningen, the Netherlands.ORCID 0000-0001-7381-6076
Abhay KoushikMax Planck School of Cognition; Stephanstrasse 1A, Leipzig, Germany.ORCID 0000-0002-7181-3215
Ottavia DipasqualeOlea Medical; La Ciotat, France.ORCID 0000-0002-2867-8222
Mitul MehtaInstitute of Psychiatry, Psychology, and Neuroscience, King's College London; London, UK.
Mara CercignaniCardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University; Cardiff, UK.
Arjun SethiInstitute of Psychiatry, Psychology, and Neuroscience, King's College London; London, UK.
Neil HarrisonCardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University; Cardiff, UK.ORCID 0000-0002-9584-3769
Štefan HoligaRoche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd; Basel, Switzerland.
Daniel UmbrichtXperimed LLC; Basel, Switzerland.
Igor YakushevDepartment of Nuclear Medicine, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich; Munich, Germany.
Suresh MuthukumaraswamySchool of Pharmacy, University of Auckland; NZ.ORCID 0000-0001-7042-3920
Anna ForsythSchool of Pharmacy, University of Auckland; NZ.ORCID 0000-0002-3283-2691
Joerg F HippRoche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd; Basel, Switzerland.
Bratislav MisicMontreal Neurological Institute, McGill University; Montreal, QC, Canada.ORCID 0000-0003-0307-2862
Svenja CaspersInstitute for Anatomy I, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf; Düsseldorf, Germany.ORCID 0000-0001-5083-4669
Julian KoenigUniversity of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy; Cologne, Germany.ORCID 0000-0003-1009-9625
Kaustubh R PatilInstitute of Neuroscience and Medicine (INM-7: Brain and Behaviour), Research Centre Jülich; Jülich, Germany.ORCID 0000-0002-0289-5480
Casey PaquolaInstitute of Neuroscience and Medicine (INM-7: Brain and Behaviour), Research Centre Jülich; Jülich, Germany.ORCID 0000-0002-0190-4103
Simon B EickhoffInstitute of Neuroscience and Medicine (INM-7: Brain and Behaviour), Research Centre Jülich; Jülich, Germany.
Juergen DukartInstitute of Neuroscience and Medicine (INM-7: Brain and Behaviour), Research Centre Jülich; Jülich, Germany.ORCID 0000-0003-0492-5644

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
Human Connectome Project for Early PsychosisU01MH109977 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI BREIER, ALAN, SHENTON, MARTHA E. · 2016 to 2020
$5.5M
NIMH NIH HHS U01 MH109977NIMH NIH HHS U54 MH091657Wellcome Trust
6 · The paper itself

Abstract

The human brain is organized into interacting functional systems. Their underlying neurobiological mechanisms remain difficult to study in vivo

Indexed as

brain networkconnectomefMRIfunctional connectivityMEGneurotransmitternoradrenalinePETresting-state

Identifiers

PMID42094566
PMCPMC13142320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.