Evidence map›Paper›PMID 42094409›Full record

ArticlebioRxiv : the preprint server for biology2026

T-cell repertoire response in individuals with post-acute sequelae of COVID-19.

Zachary Montague, Rhea M Grover, Andrew Baumgartner, Assya Trofimov, Jennifer Hadlock, Armita Nourmohammad

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zachary MontagueDepartment of Physics, University of Washington, 3910 15th Avenue Northeast, Seattle, WA 98195, USA.
Rhea M GroverDepartment of Physics, University of Washington, 3910 15th Avenue Northeast, Seattle, WA 98195, USA.
Andrew BaumgartnerInstitute for Systems Biology, Seattle, WA, USA.
Assya TrofimovDepartment of Physics, University of Washington, 3910 15th Avenue Northeast, Seattle, WA 98195, USA.
Jennifer HadlockInstitute for Systems Biology, Seattle, WA, USA.ORCID 0000-0001-6103-7606
Armita NourmohammadDepartment of Physics, University of Washington, 3910 15th Avenue Northeast, Seattle, WA 98195, USA.

Funding

Learning a molecular shape space for the adaptive immune systemR35GM142795 · NIGMS · UNIVERSITY OF WASHINGTON · PI NOURMOHAMMAD, ARMITA · 2021 to 2025
$1.8M
Modeling the dynamics and composition of T-cell receptor repertoires in post-acute sequelae of COVID-19 (PASC)R03AI175977 · NIAID · INSTITUTE FOR SYSTEMS BIOLOGY · PI HADLOCK, JENNIFER · 2024 to 2025
$195k
NIAID NIH HHS R03 AI175977NIGMS NIH HHS R35 GM142795
6 · The paper itself

Abstract

T-cells are central to SARS-CoV-2 clearance and immunological memory, yet their contribution to the persistence of post-acute sequelae of COVID-19 (PASC) remains poorly understood. The immunological features that distinguish individuals who develop PASC from those who recover fully are unresolved, in part due to the phenotypic heterogeneity of the condition and the likely multiplicity of its underlying mechanisms. Here, we profiled longitudinal bulk TCR

Identifiers

PMID42094409
PMCPMC13142483

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.