Evidence map›Paper›PMID 42094345›Full record

ArticlebioRxiv : the preprint server for biology2026

Translation Inhibiting Antibiotics Induce an asRNA Regulating Purine Metabolism in

İrem Özkan, Tim vanOpijnen, Michelle M Meyer

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

İrem ÖzkanBoston College Biology Department, Chestnut Hill MA 02445.ORCID 0000-0002-6908-1270
Tim vanOpijnenDivision of Infectious Diseases, Department of Medicine Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Michelle M MeyerBoston College Biology Department, Chestnut Hill MA 02445.ORCID 0000-0001-7014-9271

Funding

Investigating Evolutionary Constraints on Regulatory RNAR35GM158403 · NIGMS · BOSTON COLLEGE · PI Michelle Margaret Meyer · 2025 to 2026
$775k
Interactions between translation inhibiting antibiotics and diverse RNA regulatory mechanism in pathogenic bacteria affect drug sensitivityR21AI148895 · NIAID · BOSTON COLLEGE · PI MEYER, MICHELLE MARGARET, VAN OPIJNEN, TIM · 2020 to 2021
$430k
Interrogation of the sRNA regulatory network mediating virulence of Streptococcus pneumoniaeR21AI181123 · NIAID · BOSTON COLLEGE · PI MEYER, MICHELLE MARGARET · 2024 to 2025
$419k
NIAID NIH HHS R21 AI148895NIAID NIH HHS R21 AI181123NIGMS NIH HHS R35 GM158403
6 · The paper itself

Abstract

Translation inhibiting antibiotics (TIA) are an important class of antibiotics that elicit a wide variety of transcriptional responses. In this work we characterize the transcriptional responses of

Indexed as

Antisense RNAbacteriagene regulationISL3translation inhibiting antibiotics

Identifiers

PMID42094345
PMCPMC13142319

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.