Evidence map›Paper›PMID 42094338›Full record

ArticlebioRxiv : the preprint server for biology2026

Hippocampal Place Cells with NMDARs Do Not Require Excitation and Inhibition to Be Reciprocally Tuned.

Samuel Gritz, Aaron D Milstein

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Samuel GritzCenter for Advanced Biotechnology and Medicine and Department of Neuroscience and Cell Biology, Rutgers Health, Rutgers, The State University of New Jersey, Piscataway, NJ 08854.ORCID 0000-0002-8071-119X
Aaron D MilsteinCenter for Advanced Biotechnology and Medicine and Department of Neuroscience and Cell Biology, Rutgers Health, Rutgers, The State University of New Jersey, Piscataway, NJ 08854.ORCID 0000-0002-7186-5779

Funding

CRCNS: Coordinating learning by top-down gating of plasticity in dendritesR01MH135576 · NIMH · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI MILSTEIN, AARON D · 2023 to 2024
$813k
NIMH NIH HHS R01 MH135576
6 · The paper itself

Abstract

In mouse hippocampal area CA1, excitatory pyramidal neurons referred to as "place cells" fire at specific locations in spatial environments during navigation. Many of the excitatory inputs to place cells are themselves spatially tuned, and prior work has shown that synaptic plasticity at those inputs strongly contributes to a selective increase in excitatory synaptic conductance when an animal is inside a cell's "place field." It is less clear whether inhibitory inputs to place cells vary with spatial position. Recent studies have investigated whether place cells receive spatially tuned inhibitory conductances by recording place cell activity

Identifiers

PMID42094338
PMCPMC13142514

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.