ArticleFrontiers in bioengineering and biotechnology2026
Assessing cytotoxic and antibacterial effects of high dispersion-stable sub-5 nm silver particles fabricated by ionic liquid-mediated electrochemical synthesis.
Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Exploring nanoscale metal particles with high colloidal stability and antibacterial activity is critical for advancing biomedicine in the context of antibiotic resistance. In this study, ultra-small silver nanoparticles (Ag-NPs) with sub-5 nm were synthesized in a one-step electrochemical route in an ionic-liquid-containing electrolyte. The resulting colloid of Ag-NPs remained for more than 400 days without precipitation and ultraviolet-visible spectral shift. Dynamic light scattering gives an average hydrated particle diameter of 2.8 nm and a Zeta potential of -0.6 mV. Cell viability and cytotoxicity results showed high cell compatibility of Ag-NPs at ≤ 4 μg/mL and obvious cell death at 16 μg/mL. The antibacterial potency of Ag-NPs was evaluated using the Oxford cup method and the broth dilution test. The minimum inhibitory concentration of Ag-NPs against the Gram-positive bacteria
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