Evidence map›Paper›PMID 42094236›Full record

ArticleHuman mutation2026

Zhi Li, Dedong Wang, Jinbin Chen, Di Wu, Shuyu Tang, Jinyi Huang, Yibin Deng, Xinhua Wang, Fuman Qiu, Lei Yang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human mutation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Human mutation · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhi LiThe State Key Lab of Respiratory Disease, The First Affiliated Hospital, The Institute for Chemical Carcinogenesis, School of Public Health, Guangzhou Medical University, Guangzhou, Guangdong, China, gzhmc.edu.cn.ORCID https://orcid.org/0009-0008-1277-7796
Dedong WangThe State Key Lab of Respiratory Disease, The First Affiliated Hospital, The Institute for Chemical Carcinogenesis, School of Public Health, Guangzhou Medical University, Guangzhou, Guangdong, China, gzhmc.edu.cn.
Jinbin ChenThe State Key Lab of Respiratory Disease, The First Affiliated Hospital, The Institute for Chemical Carcinogenesis, School of Public Health, Guangzhou Medical University, Guangzhou, Guangdong, China, gzhmc.edu.cn.
Di WuThe State Key Lab of Respiratory Disease, The First Affiliated Hospital, The Institute for Chemical Carcinogenesis, School of Public Health, Guangzhou Medical University, Guangzhou, Guangdong, China, gzhmc.edu.cn.
Shuyu TangGuangzhou Women and Children's Medical Center, Guanzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, China, gzhmc.edu.cn.
Jinyi HuangThe State Key Lab of Respiratory Disease, The First Affiliated Hospital, The Institute for Chemical Carcinogenesis, School of Public Health, Guangzhou Medical University, Guangzhou, Guangdong, China, gzhmc.edu.cn.
Yibin DengCentre for Medical Laboratory Science, the Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China, ymcn.gx.cn.ORCID https://orcid.org/0000-0002-0869-0400
Xinhua WangInstitute of Basic Medicine, Institute of Public Health, Gansu University of Chinese Medicine, Lanzhou, Gansu, China, gszy.edu.cn.
Fuman QiuThe State Key Lab of Respiratory Disease, The First Affiliated Hospital, The Institute for Chemical Carcinogenesis, School of Public Health, Guangzhou Medical University, Guangzhou, Guangdong, China, gzhmc.edu.cn.
Lei YangThe State Key Lab of Respiratory Disease, The First Affiliated Hospital, The Institute for Chemical Carcinogenesis, School of Public Health, Guangzhou Medical University, Guangzhou, Guangdong, China, gzhmc.edu.cn.
Jiachun LuThe State Key Lab of Respiratory Disease, The First Affiliated Hospital, The Institute for Chemical Carcinogenesis, School of Public Health, Guangzhou Medical University, Guangzhou, Guangdong, China, gzhmc.edu.cn.ORCID https://orcid.org/0000-0002-6189-826X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Energy metabolism reprogramming of cancer cells with the abnormal glycolytic capacity represents a novel direction of tumor therapy. Nevertheless, there is a lack of evidence linking genetic variations in glycolysis-related genes to the risk and clinical progression of lung cancer (LC). This study is aimed at clarifying the genetic effect of glycolytic pathway-related genes on the occurrence and development of LC. Methods: In this two-stage case-control study, we enrolled 300 LC patients and 600 healthy controls, as well as 1248 case-control pairs from several hospitals in Guangzhou, to evaluate the association between the genetic variations of glycolysis-related genes ( Results: Only Conclusion: Altogether,

Indexed as

Genetic Predisposition to DiseaseGlucose Transporter Type 1Lung NeoplasmsPolymorphism, Single NucleotideAgedAllelesCase-Control StudiesFemaleGenetic Association StudiesGenotypeHumansMaleMiddle AgedPrognosisRisk FactorsGlucose Transporter Type 1SLC2A1 protein, humanglucose transporter 1glycolyticlung cancerrs1385129single nucleotide polymorphism

Identifiers

PMID42094236
PMCPMC13139712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.