Evidence map›Paper›PMID 42094157›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Estimated Impacts of Rotavirus Vaccine Recommendation Changes in the U.S.

Ernest O Asare, Jiye Kwon, Melanie H Chitwood, Stephanie Perniciaro, Gregg S Gonsalves, Virginia E Pitzer

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ernest O AsareDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health; New Haven, CT, USA.
Jiye KwonDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health; New Haven, CT, USA.ORCID 0000-0002-2707-3547
Melanie H ChitwoodDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health; New Haven, CT, USA.
Stephanie PerniciaroDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health; New Haven, CT, USA.
Gregg S GonsalvesDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health; New Haven, CT, USA.
Virginia E PitzerDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health; New Haven, CT, USA.

Funding

Modeling the impact and cost-effectiveness of next-generation rotavirus vaccine strategies in low- and middle-income countriesR01AI112970 · NIAID · YALE UNIVERSITY · PI PITZER, VIRGINIA E · 2015 to 2024
$4.1M
NIAID NIH HHS R01 AI112970
6 · The paper itself

Abstract

In January 2026, the United States Department of Health and Human Services downgraded the recommendation for infant immunization with rotavirus vaccine to one of shared clinical decision-making. We use a validated model for the transmission dynamics of rotavirus to predict the magnitude and timing of increases in the number of rotavirus hospitalizations in the US and in representative states given possible decreases in vaccine coverage. Rotavirus hospitalizations are likely to increase within two to three years following a drop in vaccine coverage, resulting in over 200,000 hospitalizations between July 2026-June 2031 if coverage were to drop to 20%. The burden is likely to fall disproportionately on southern states that currently experience higher rates of rotavirus hospitalization.

Identifiers

PMID42094157
PMCPMC13142563

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.