Evidence map›Paper›PMID 42094079›Full record

ReviewInternational journal of cardiology. Congenital heart disease2026

Advancements in pacing and ICD technologies: Potential implications for complex congenital heart disease in adults.

Lorenzo Caratti di Lanzacco, Nikolaos Vogiatzakis, Davide Fabbricatore, Charles Yao-Cheng Ho, Tsveta Rahneva, Michael Athanasios Gatzoulis, Tom Wong

Abstract readReview
In one paragraph

Review in International journal of cardiology. Congenital heart disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lorenzo Caratti di LanzaccoRoyal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
Nikolaos VogiatzakisRoyal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
Davide FabbricatoreRoyal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
Charles Yao-Cheng HoRoyal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
Tsveta RahnevaRoyal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
Michael Athanasios GatzoulisRoyal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
Tom WongRoyal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adults with congenital heart disease (ACHD) represent a rapidly growing population with a high burden of bradyarrhythmias and ventricular arrhythmias requiring cardiac implantable electronic devices. However, conventional transvenous pacing and defibrillator systems often present important challenges in this population due to complex anatomy, limited venous access, intracardiac shunts, and the cumulative risk of lead-related complications over a patient's lifetime. Recent technological advances-including conduction system pacing, leadless pacemakers, subcutaneous and extravascular implantable cardioverter-defibrillators, and emerging modular pacing-defibrillator platforms-have expanded the range of device strategies available for ACHD patients. These innovations aim to reduce intravascular hardware, improve physiological ventricular activation, and enable device therapies tailored to complex congenital anatomy. However, the evidence supporting both conventional and emerging technologies in ACHD patients remains limited and is derived largely from small observational studies and registry data. In addition, the substantial heterogeneity of congenital heart diseases and their prior surgical repair complicates extrapolation of outcomes across patient subgroups. Careful patient selection, anatomical assessment, and consideration of long-term device management therefore remain central to clinical decision-making. In this narrative review, we summarise recent developments in pacing and defibrillator technologies and discuss their potential implications for adults with congenital heart disease. To support clinical decision-making, we also propose a pragmatic ACHD-specific device-selection algorithm integrating anatomical, electrophysiological, and long-term management considerations.

Indexed as

Adults congenital heart diseaseConduction system pacingLeadless pacemaker

Identifiers

PMID42094079
PMCPMC13141987

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.