ArticleResearch square2026
Clinical outcomes of sub-millisievert CT evaluation of congenital chest wall deformity using photon counting CT: a new standard of care?
Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
15 authors.
Funding
Abstract
Background: Pectus excavatum is the most common congenital chest wall deformity and is typically treated surgically. Disease severity is commonly assessed using the CT-derived Haller Index (HI), creating opportunities to reduce radiation exposure in pediatric patients. Photon-counting detector CT (PCD-CT) enables substantial dose reduction; however, the clinical impact of sub-millisievert (sub-mSv) imaging has not been well established. Objective: To evaluate the impact of sub-millisievert (sub-mSv) PCD-CT scans on clinical outcomes in the preoperative assessment of congenital pectus deformities. Methods: This retrospective study included patients with congenital pectus deformities treated at a single institution. Introduction of a PCD-CT system and dose-optimized protocols enabled comparison between standard-dose (SD) and sub-mSv CT cohorts. Demographic and clinical characteristics, including age, body mass index (BMI), HI, and effective diameter, were compared, along with radiation exposure metrics and postoperative clinical outcomes. Results: There were no significant differences between the SD and sub-mSv cohort in age (unadjusted/adjusted p = 0.32/1), HI (unadjusted p = 0.27/1), BMI (unadjusted p = 0.44/1), or effective diameter (unadjusted p = 0.22/1). Median sub-mSv protocol CTDI Conclusion: Sub-mSv PCD-CT provides diagnostic image quality for preoperative evaluation of congenital chest wall deformities while reducing radiation exposure to levels comparable to a chest radiograph. These findings support broader adoption of low-dose PCD-CT in pediatric chest imaging and emphasize the importance of outcome-based validation of dose reduction strategies.
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