Evidence map›Paper›PMID 42094038›Full record

ArticleResearch square2026

Cognitive Assessment for Neuropsychological Impairments in Dogs (CANID): An Efficient, Repeatable, and Sensitive Evaluation for Age-related Cognitive Dysfunction.

Stephanie H Hargrave, Emily E Bray, Lorelei R Switzer, Stephanie McGrath, Gene E Alexander, Theadora Block, Elizabeth Carranza, Naomi Chao, Laura E L C Douglas, Janet Galante and 12 more

Abstract readPreprint
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Stephanie H HargraveUniversity of Arizona.
Emily E BrayUniversity of Arizona.
Lorelei R SwitzerUniversity of Arizona.
Stephanie McGrathColorado State University.
Gene E AlexanderUniversity of Arizona.
Theadora BlockCanine Companions.
Elizabeth CarranzaUniversity of Arizona.
Naomi ChaoUniversity of Arizona.
Laura E L C DouglasCanine Companions.
Janet GalanteSit! Stay! Play!
Emily HilyardSit! Stay! Play!
Dara JonkoskiUniversity of Arizona.
Brenda S KennedyCanine Companions.
Emma KristalUniversity of Arizona.
Julie A MorenoColorado State University.
Daniel E L PromislowTufts University.
David A RaichlenUniversity of Southern California.
Noah StetsonUniversity of Arizona.
Kaitlyn TeresoUniversity of Arizona.
Nova VogelUniversity of Arizona.
Dog Aging Project Consortium
Evan L MacLeanUniversity of Arizona.

Funding

The Dog Aging Project: Genetic and Environmental Determinants of Healthy Aging in Companion Dogs Competitive RevisionU19AG057377 · NIA · UNIVERSITY OF WASHINGTON · PI PROMISLOW, DANIEL EDWARD · 2018 to 2023
$29.0M
Developing the Privately Owned Companion Dog as a Model for Alzheimers DiseaseR24AG073137 · NIA · UNIVERSITY OF WASHINGTON · PI KEENE, CHRISTOPHER DIRK, MCGRATH, STEPHANIE · 2021 to 2024
$5.1M
NIA NIH HHS R24 AG073137NIA NIH HHS U19 AG057377
6 · The paper itself

Abstract

We introduce the Cognitive Assessment for Neuropsychological Impairments in Dogs (CANID), a functional evaluation consisting of three cognitive tasks that measure aspects of memory and executive function. CANID can be implemented in a single ~ 40-minute evaluation, was designed for studies of cognitive aging in community dwelling dogs, and is sensitive to mid-life mild cognitive dysfunction. We developed a scoring system using a baseline sample (N = 239) and repeat testing at six (N = 140) and twelve (N = 118) month follow-up. Overall CANID scores had substantial repeatability at six (ICC = 0.63, 95% CI [0.51, 0.72]) and twelve (ICC = 0.59, 95% CI [0.47, 0.70]) months, as did all task-specific subscores. CANID scores at 6-month follow-up suggested modest practice effects (0.23 SD improvement in overall score relative to baseline), similar to those reported in human studies, but we did not find evidence for practice effects at one-year follow-up. To facilitate CANID's use, we provide detailed protocols, video libraries, data recording instruments, experimenter training guidelines, and R code for scoring in an Open Science Framework repository.

Identifiers

PMID42094038
PMCPMC13142635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.