Evidence map›Paper›PMID 42094031›Full record

ArticleObstetric medicine2026

Impact of tighter glycaemic targets on pregnancy outcomes in a multi-ethnic cohort with gestational diabetes: A retrospective, single centre observational study.

Mohammed Sb Huda, Niki Margari, Nafisa Islam, Hannah Jaumdally, Kate Wiles, Rehan Khan, Peter Jacob, Elena Greco, Stamatina Iliodromiti, Anita Sanghi and 1 more

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Article in Obstetric medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mohammed Sb HudaDepartment of Diabetes & Metabolism, Royal London Hospital, London, UK.ORCID https://orcid.org/0000-0001-7303-199X
Niki MargariDepartment of Diabetes & Metabolism, Royal London Hospital, London, UK.
Nafisa IslamDepartment of Diabetes & Metabolism, Royal London Hospital, London, UK.ORCID https://orcid.org/0000-0002-7459-0467
Hannah JaumdallyDepartment of Diabetes & Metabolism, Royal London Hospital, London, UK.
Kate WilesDepartment of Obstetrics, Royal London Hospital, London, UK.ORCID https://orcid.org/0000-0003-0617-8144
Rehan KhanDepartment of Obstetrics, Royal London Hospital, London, UK.
Peter JacobDepartment of Diabetes & Metabolism, Royal London Hospital, London, UK.
Elena GrecoWomen's Health Research Unit, Wolfson Institute of Population Health, Queen Mary University of London, London, UK.
Stamatina IliodromitiWomen's Health Research Unit, Wolfson Institute of Population Health, Queen Mary University of London, London, UK.
Anita SanghiDepartment of Obstetrics, Royal London Hospital, London, UK.
Shakila ThangaratinamWomen's Health Research Unit, Wolfson Institute of Population Health, Queen Mary University of London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: To determine the impact of tighter glycaemic targets for gestational diabetes. Methods: Retrospective data analysis before and after introducing tighter glucose targets. Results: In 2265 pregnancies there was no change in large-for-gestational age babies (Odds ratio (OR) 1.1; 95% Confidence interval (CI) 0.8-1.6) and macrosomia (OR 1.0; 95% CI 0.6-1.7) following tighter glucose targets. Gestational hypertension (OR 0.4; 95% CI 0.2-0.7), spontaneous vaginal birth (OR 0.6; 95% CI 0.4-0.9) reduced and pharmacological treatment increased (OR 2.2; 95% CI 1.7-2.8).Composite adverse neonatal outcome (perinatal death, shoulder dystocia, fracture, nerve palsy) (OR 0.6; CI 0.02-14.2 p = 0.76)), Apgar<7 at 5 min, neonatal hypoglycaemia, respiratory distress syndrome or neonatal unit admission did not change but neonatal jaundice was reduced (OR 0.4; 95% CI 0.2-0.8). Conclusions: Tighter glycaemic targets had no impact on large-for-gestational age babies or composite adverse neonatal outcomes. There was reduced spontaneous vaginal birth, gestational hypertension, neonatal jaundice and increased pharmacological treatment.

Indexed as

ethnically diverse populationGestational diabetesglycaemic targetsmaternal and fetal outcomessingle centre

Identifiers

PMID42094031
PMCPMC13139312

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.